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PTN Antibody (monoclonal) (M01)

PTN Antibody (monoclonal) (M01)

Item no.	ABC-AT3491a
Manufacturer	Abcepta
Amount	100 ug
Category	Neuroscience Molecular Targets for Neuroscience Antibodies Immunohistochemistry Western Blot Primary Antibodies
Type	Antibody Monoclonal
Format	Liquid
Applications	WB, IHC
Clone	5C3
Specific against	Human (Homo sapiens)
Host	Mouse
Isotype	IgG1 Kappa
Citations	1.Expression of the growth factor pleiotrophin and its receptor protein tyrosine phosphatase beta/zeta in the serum, cartilage and subchondral bone of patients with osteoarthritis.Kaspiris A, Mikelis C, Heroult M, Khaldi L, Grivas TB, Kouvaras I, Dangas S, Vasiliadis E, Liote F, Courty J, Papadimitriou E.Joint Bone Spine. 2013 Jan 17. doi:pii: S1297-319X(12)00296-5. 10.1016/j.jbspin.2012.10.024. [Epub ahead of print]2.Interplay between ?v?]3 Integrin and Nucleolin Regulates Human Endothelial and Glioma Cell Migration.Koutsioumpa M, Polytarchou C, Courty J, Zhang Y, Kieffer N, Mikelis C, Skandalis SS, Hellman U, Iliopoulos D, Papadimitriou E.J Biol Chem. 2013 Jan 4;288(1):343-54. doi: 10.1074/jbc.M112.387076. Epub 2012 Nov 16.3.Pleiotrophin promotes microglia proliferation and secretion of neurotrophic factors by activating extracellular signal-regulated kinase 1/2 pathway.Miao J, Ding M, Zhang A, Xiao Z, Qi W, Luo N, Di W, Tao Y, Fang Y.Neurosci Res. 2012 Sep 18. pii: S0168-0102(12)00173-3. doi: 10.1016/j.neures.2012.09.001. [Epub ahead of print]4.Implications of pleiotrophin in human PC3 prostate cancer cell growth in vivo.Tsirmoula S, Dimas K, Hatziapostolou M, Lamprou M, Ravazoula P, Papadimitriou E.Cancer Sci. 2012 Oct;103(10):1826-32. doi: 10.1111/j.1349-7006.2012.02383.x. Epub 2012 Aug 14.5.A peptide corresponding to the C-terminal region of pleiotrophin inhibits angiogenesis in vivo and in vitro.Mikelis C, Lamprou M, Koutsioumpa M, Koutsioubas AG, Spyranti Z, Zompra AA, Spiliopoulos N, Vradis AA, Katsoris P, Spyroulias GA, Cordopatis P, Courty J, Papadimitriou E.J Cell Biochem. 2011 Feb 22. doi: 10.1002/jcb.23066. [Epub ahead of print]6.Integrin {alpha}{nu}{beta}3 is a pleiotrophin receptor required for pleiotrophin-induced endothelial cell migration through receptor protein tyrosine phosphatase {beta}/{zeta}.Mikelis C, Sfaelou E, Koutsioumpa M, Kieffer N, Papadimitriou E.FASEB J. 2009 May;23(5):1459-69. Epub 2009 Jan 13.7.Aprotinin stimulates angiogenesis and human endothelial cell migration through the growth factor pleiotrophin and its receptor protein tyrosine phosphatase beta/zeta.Koutsioumpa M, Hatziapostolou M, Mikelis C, Koolwijk P, Papadimitriou E.Eur J Pharmacol. 2009 Jan 14;602(2-3):245-9. Epub 2008 Dec 3.
NCBI	NP_002816.1
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Similar products	PTN, Pleiotrophin, HBNF1, NEGF1, Heparin-binding brain mitogen, Heparin-binding growth factor 8, Heparin-binding growth-associated molecule, Heparin-binding neurite outgrowth-promoting factor 1, Osteoblast-specific factor 1, HB-GAM, HBGF-8, OSF-1, HBNF-1, HBBM
Available
Manufacturer - Targets	PTN (NP_002816, 45 a.a. ~ 154 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Clonality	Monoclonal
Gene Name	PTN
Subtitle	Mouse monoclonal antibody raised against a partial recombinant PTN.
Reactivity	H
Formulation	Clear, colorless solution in phosphate buffered saline, pH 7.2 .
Dilution	WB: 1:500~1000 WB: 1:500~1000 WB: 1:500~1000 IHC
Org Accession	NP_002816
Gene Description	pleiotrophin
Antigen Type	Recombinant Protein
Manufacturer - Alias	Pleiotrophin, PTN, Heparin-binding brain mitogen, HBBM, Heparin-binding growth factor 8, HBGF-8, Heparin-binding growth-associated molecule, HB-GAM, Heparin-binding neurite outgrowth-promoting factor 1, HBNF-1, Osteoblast-specific factor 1, OSF-1, PTN, HBNF1, NEGF1
Manufacturer - Similar	Pleiotrophin, PTN, Heparin-binding brain mitogen, HBBM, Heparin-binding growth factor 8, HBGF-8, Heparin-binding growth-associated molecule, HB-GAM, Heparin-binding neurite outgrowth-promoting factor 1, HBNF-1, Osteoblast-specific factor 1, OSF-1, PTN, HBNF1, NEGF1

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ug

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Delivery expected until 3/5/2026

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