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RAB27A Antibody (monoclonal) (M01)

RAB27A Antibody (monoclonal) (M01)

Item no.	ABC-AT3517a
Manufacturer	Abcepta
Amount	100 ug
Category	Antibodies Cell Biology Cytoskeleton Western Blot ELISA Primary Antibodies Immunostaining small GTPases Rab Subfamily
Type	Antibody Monoclonal
Format	Liquid
Applications	WB, ELISA
Clone	4C1
Specific against	Human (Homo sapiens)
Host	Mouse
Isotype	IgG1 Kappa
Citations	Functional characterization of two RAB27A missense mutations found in Griscelli syndrome type 2. Ohbayashi N, et al. Pigment Cell Melanoma Res, 2010 Jun. PMID 20370853.New genetic associations detected in a host response study to hepatitis B vaccine. Davila S, et al. Genes Immun, 2010 Apr. PMID 20237496.Genome-wide analysis of chromosomal alterations in patients with esophageal squamous cell carcinoma exposed to tobacco and betel quid from high-risk area in India. Chattopadhyay I, et al. Mutat Res, 2010 Feb 2. PMID 20083228.Clinical presentation of Griscelli syndrome type 2 and spectrum of RAB27A mutations. Meeths M, et al. Pediatr Blood Cancer, 2010 Apr. PMID 19953648.Different NK cell-activating receptors preferentially recruit Rab27a or Munc13-4 to perforin-containing granules for cytotoxicity. Wood SM, et al. Blood, 2009 Nov 5. PMID 19704116.
NCBI	NP_004571.2,NP_899057.1,NP_899058.1,NP_899059.1
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Ras-related protein Rab-27A,Rab-27,GTP-binding protein Ram,RAB27A,RAB27
Similar products	RAB27A, RAB27, Ras-related protein Rab-27A, GTP-binding protein Ram, Rab-27
Available
Manufacturer - Targets	RAB27A (NP_004571, 122 a.a. ~ 221 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Bio Background	The protein encoded by this gene belongs to the small GTPase superfamily, Rab family. The protein is membrane-bound and may be involved in protein transport and small GTPase mediated signal transduction. Mutations in this gene are associated with Griscelli syndrome type 2. Alternative splicing occurs at this locus and four transcript variants encoding the same protein have been identified.
Clonality	Monoclonal
Gene Name	RAB27A
Subtitle	Mouse monoclonal antibody raised against a partial recombinant RAB27A.
Reactivity	H
Antigen Source	Human: ~~ Positive
Formulation	Clear, colorless solution in phosphate buffered saline, pH 7.2 .
Dilution	WB: 1:500~1000 WB: 1:500~1000 E
Org Accession	NP_004571
Gene Description	RAB27A, member RAS oncogene family
Gene Summary	The protein encoded by this gene belongs to the small GTPase superfamily, Rab family. The protein is membrane-bound and may be involved in protein transport and small GTPase mediated signal transduction. Mutations in this gene are associated with Griscelli syndrome type 2. Alternative splicing occurs at this locus and four transcript variants encoding the same protein have been identified. [provided by RefSeq
Antigen Type	Recombinant Protein

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ug

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Delivery expected until 1/1/2026

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