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S100A8 Antibody (monoclonal) (M01)

S100A8 Antibody (monoclonal) (M01)

Item no.	ABC-AT3763a
Manufacturer	Abcepta
Amount	100 ug
Category	Antibodies Primary Antibodies
Type	Antibody Primary
Format	Clear, colorless solution in phosphate buffered saline, pH 7.2 .
Applications	WB
Clone	2H2
Specific against	other
Host	Mouse
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	S100A8, N-terminally processed, MRP8, p8, CAGA, CFAG, S100 calcium-binding protein A8, Calgranulin-A, Calprotectin L1L subunit, Cystic fibrosis antigen, Leukocyte L1 complex light chain, Migration inhibitory factor-related protein 8, MRP-8, Protein S100-A8, Urinary stone protein band A
Available
Primary Accession	P05109
Antigen Type	Recombinant Protein
Application	WB
Bio Background	The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in the inhibition of casein kinase and as a cytokine. Altered expression of this protein is associated with the disease cystic fibrosis.
Bio References	iPLA2, a novel determinant in Ca2+- and phosphorylation-dependent S100A8/A9 regulated NOX2 activity. Schenten V, et al. Biochim Biophys Acta, 2010 Jul. PMID 20219570.Evaluation of calprotectin level in intestinal content as an early marker for graft rejection. Cagnola H, et al. Transplant Proc, 2010 Jan-Feb. PMID 20172281.S100A8/A9 induces autophagy and apoptosis via ROS-mediated cross-talk between mitochondria and lysosomes that involves BNIP3. Ghavami S, et al. Cell Res, 2010 Mar. PMID 19935772.S100A8/A9: a mediator of severe asthma pathogenesis and morbidity? Halayko AJ, et al. Can J Physiol Pharmacol, 2009 Oct. PMID 19898558.Calprotectin--a novel marker of obesity. Mortensen OH, et al. PLoS One, 2009 Oct 12. PMID 19823685.
Clonality	Monoclonal
Gene ID	6279
Gene Name	S100A8 (HGNC:10498)
Subtitle	Mouse monoclonal antibody raised against a full length recombinant S100A8.
Reactivity	H
Legend image 1	Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (35.97 KDa) .
Type image 1	WB
Dilution image 1	1:500~1000
Other Accession	BC005928
Isotype	IgG2a Kappa
Target/Specificity	S100A8 (AAH05928.1, 1 a.a. ~ 93 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
NCBI Accession	NP_002955.2
	Clone: 2H2
Org Accession	AAH05928.1
Concentration	1 mg/ml
Gene Description	S100 calcium binding protein A8
Gene Summary	The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in the inhibition of casein kinase and as a cytokine. Altered expression of this protein is associated with the disease cystic fibrosis. [provided by RefSeq

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ug

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Delivery expected until 10/2/2025

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