Comparison

SERPINA3 Antibody (monoclonal) (M01)

Item no. ABC-AT3818a
Manufacturer Abcepta
Amount 50 ug
Category
Type Antibody Monoclonal
Format Liquid
Applications WB, IP, IHC
Clone 1000000
Specific against Human (Homo sapiens)
Host Mouse
Isotype IgG1 Kappa
Citations Variation at the NFATC2 Locus Increases the Risk of Thiazolinedinedione-Induced Edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) Study. Bailey SD, et al. Diabetes Care, 2010 Jul 13. PMID 20628086. Is there an association of regulatory region polymorphism in the alpha-1-antichymotrypsin gene with sporadic Alzheimer's disease in the northern Han-Chinese population? Yu G, et al. J Clin Neurosci, 2010 Jun. PMID 20378355. Proteomic analysis of plasma from patients undergoing coronary artery bypass grafting reveals a protease/antiprotease imbalance in favor of the serpin alpha1-antichymotrypsin. Banfi C, et al. J Proteome Res, 2010 May 7. PMID 20302328. alpha(1)-Antichymotrypsin deficiency associated with liver cirrhosis. Ortega L, et al. Pediatr Int, 2010 Feb. PMID 20158662. Inhibition of heat- and chemical-induced aggregation of various proteins reveals chaperone-like activity of the acute-phase component and serine protease inhibitor human alpha(1)-antitrypsin. Zsila F. Biochem Biophys Res Commun, 2010 Mar 5. PMID 20117085.
NCBI NP_001076.2
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Alias Alpha-1-antichymotrypsin,ACT,Cell growth-inhibiting gene 24/25 protein,Serpin A3,Alpha-1-antichymotrypsin His-Pro-less,SERPINA3,AACT
Similar products SERPINA3, AACT, ACT, Alpha-1-antichymotrypsin, Cell growth-inhibiting gene 24/25 protein, Serpin A3, Alpha-1-antichymotrypsin His-Pro-less
Available
Manufacturer - Targets
SERPINA3 (AAH03559, 25 a.a. ~ 423 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Bio Background
The protein encoded by this gene is a plasma protease inhibitor and member of the serine protease inhibitor class. Polymorphisms in this protein appear to be tissue specific and influence protease targeting. Variations in this protein's sequence have been implicated in Alzheimer's disease, and deficiency of this protein has been associated with liver disease. Mutations have been identified in patients with Parkinson disease and chronic obstructive pulmonary disease.
Clonality
Monoclonal
Gene Name
SERPINA3
Subtitle
Mouse monoclonal antibody raised against a full length recombinant SERPINA3.
Reactivity
H
Antigen Source
Human: ~~ Positive
Formulation
Clear, colorless solution in phosphate buffered saline, pH 7.2 .
Dilution
IP
WB: 1:500~1000
WB: 1:500~1000
IHC
Org Accession
AAH03559
Gene Description
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
Gene Summary
The protein encoded by this gene is a plasma protease inhibitor and member of the serine protease inhibitor class. Polymorphisms in this protein appear to be tissue specific and influence protease targeting. Variations in this protein' s sequence have been implicated in Alzheimer' s disease, and deficiency of this protein has been associated with liver disease. Mutations have been identified in patients with Parkinson disease and chronic obstructive pulmonary disease. [provided by RefSeq
Antigen Type
Recombinant Protein

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 50 ug
Available: In stock
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