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SHC1 Antibody (monoclonal) (M01)

SHC1 Antibody (monoclonal) (M01)

Item no.	ABC-AT3880a
Manufacturer	Abcepta
Amount	100 ug
Category	Neuroscience Molecular Targets for Neuroscience Antibodies Immunohistochemistry Western Blot ELISA Immunofluorescence Primary Antibodies Immunostaining
Type	Antibody Monoclonal
Format	Liquid
Applications	WB, IF, IHC, ELISA
Clone	3F4
Specific against	Human (Homo sapiens)
Host	Mouse
Isotype	IgG1 Kappa
Citations	Oxidative stress alters the regulatory control of p66Shc and Akt in PINK1 deficient cells. Maj MC, et al. Biochem Biophys Res Commun, 2010 Aug 27. PMID 20637729.Tarp regulates early Chlamydia-induced host cell survival through interactions with the human adaptor protein SHC1. Mehlitz A, et al. J Cell Biol, 2010 Jul 12. PMID 20624904.Hyperglycemia-induced p66shc inhibits insulin-like growth factor I-dependent cell survival via impairment of Src kinase-mediated phosphoinositide-3 kinase/AKT activation in vascular smooth muscle cells. Xi G, et al. Endocrinology, 2010 Aug. PMID 20534722.Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. Rose JE, et al. Mol Med, 2010 Jul-Aug. PMID 20379614.p66Shc is indispensable for phenethyl isothiocyanate-induced apoptosis in human prostate cancer cells. Xiao D, et al. Cancer Res, 2010 Apr 15. PMID 20354186.
NCBI	NP_001123512.1,NP_001123513.1,NP_001189788.1,NP_003020.2,NP_892113.4
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	SHC-transforming protein 1,SHC-transforming protein 3,SHC-transforming protein A,Src homology 2 domain-containing-transforming protein C1,SH2 domain protein C1,SHC1,SHC,SHCA
Similar products	SHC1, SHC-transforming protein 1, SHC-transforming protein A, Src homology 2 domain-containing-transforming protein C1, SHC, SHCA, SHC-transforming protein 3, SH2 domain protein C1
Available
Manufacturer - Targets	SHC1 (AAH33925, 171 a.a. ~ 280 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Clonality	Monoclonal
Gene Name	SHC1
Subtitle	Mouse monoclonal antibody raised against a partial recombinant SHC1.
Reactivity	H
Antigen Source	Human: ~~ Positive
Formulation	Clear, colorless solution in phosphate buffered saline, pH 7.2 .
Dilution	IF WB: 1:500~1000 WB: 1:500~1000 IHC E
Org Accession	AAH33925
Gene Description	SHC (Src homology 2 domain containing) transforming protein 1
Antigen Type	Recombinant Protein

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ug

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Delivery expected until 1/1/2026

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