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SMAD6 Antibody (monoclonal) (M07)

SMAD6 Antibody (monoclonal) (M07)

Item no.	ABC-AT3946a
Manufacturer	Abcepta
Amount	100 ug
Category	Neuroscience Neuroinflammation Antibodies Western Blot ELISA Primary Antibodies Immunostaining
Type	Antibody Monoclonal
Format	Liquid
Applications	WB, ELISA
Clone	4F4
Specific against	Human (Homo sapiens)
Host	Mouse
Isotype	IgG2b Kappa
Citations	Smad2 and Smad6 as predictors of overall survival in oral squamous cell carcinoma patients. Mangone FR, et al. Mol Cancer, 2010 May 12. PMID 20462450.Association of TGFBR2 polymorphism with risk of sudden cardiac arrest in patients with coronary artery disease. Tseng ZH, et al. Heart Rhythm, 2009 Dec. PMID 19959123.Downregulation of SMAD2, 4 and 6 mRNA and TGFbeta receptor I mRNA in lesional and non-lesional psoriatic skin. Yu H, et al. Acta Derm Venereol, 2009. PMID 19688145.Bone mass effects of a Smad6 gene polymorphism in Japanese postmenopausal women. Urano T, et al. J Bone Miner Metab, 2009. PMID 19277452.A new nonsense mutation of SMAD8 associated with pulmonary arterial hypertension. Shintani M, et al. J Med Genet, 2009 May. PMID 19211612.
NCBI	NP_001136333.1,NP_005576.3
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Mothers against decapentaplegic homolog 6,MAD homolog 6,Mothers against DPP homolog 6,SMAD family member 6,SMAD 6,Smad6,hSMAD6,SMAD6,MADH6
Similar products	Smad6, SMAD6, MADH6, Mothers against decapentaplegic homolog 6, SMAD family member 6, MAD homolog 6, Mothers against DPP homolog 6, SMAD 6, hSMAD6
Available
Manufacturer - Targets	SMAD6 (NP_005576, 285 a.a. ~ 384 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Bio Background	The protein encoded by this gene belongs to the SMAD family of proteins, which are related to Drosophila 'mothers against decapentaplegic' (Mad) and C. elegans Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein functions in the negative regulation of BMP and TGF-beta/activin-signalling. Multiple transcript variants encoding different isoforms have been found for this gene.
Clonality	Monoclonal
Gene Name	SMAD6
Subtitle	Mouse monoclonal antibody raised against a partial recombinant SMAD6.
Reactivity	H
Formulation	Clear, colorless solution in phosphate buffered saline, pH 7.2 .
Concentration	1 mg/ml
Dilution	WB: 1:500~1000 WB: 1:500~1000 E
Org Accession	NP_005576
Gene Description	SMAD family member 6
Gene Summary	The protein encoded by this gene belongs to the SMAD family of proteins, which are related to Drosophila ' mothers against decapentaplegic' (Mad) and C. elegans Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein functions in the negative regulation of BMP and TGF-beta/activin-signalling. Multiple transcript variants encoding different isoforms have been found for this gene
Antigen Type	Recombinant Protein

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ug

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Delivery expected until 1/1/2026

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