SP110 Antibody (monoclonal) (M03)

Item no.	ABC-AT4008a
Manufacturer	Abcepta
Amount	100 ug
Category	Metabolism Diabetes Antibodies Western Blot ELISA Immunofluorescence Primary Antibodies Immunostaining
Type	Antibody Monoclonal
Format	Liquid
Applications	WB, IF, ELISA
Clone	2G10
Specific against	Human (Homo sapiens)
Host	Mouse
Isotype	IgG2a Kappa
Citations	Degree of predicted minor histocompatibility antigen mismatch correlates with poorer clinical outcomes in nonmyeloablative allogeneic hematopoietic cell transplantation. Larsen ME, et al. Biol Blood Marrow Transplant, 2010 Oct. PMID 20353833.Genetic susceptibility variants for chronic lymphocytic leukemia. Slager SL, et al. Cancer Epidemiol Biomarkers Prev, 2010 Apr. PMID 20332261.Large-scale candidate gene analysis of spontaneous clearance of hepatitis C virus. Mosbruger TL, et al. J Infect Dis, 2010 May 1. PMID 20331378.Polymorphisms in IL-1beta, vitamin D receptor Fok1, and Toll-like receptor 2 are associated with extrapulmonary tuberculosis. Motsinger-Reif AA, et al. BMC Med Genet, 2010 Mar 2. PMID 20196868.A genome-wide association study identifies six susceptibility loci for chronic lymphocytic leukemia. Di Bernardo MC, et al. Nat Genet, 2008 Oct. PMID 18758461.
NCBI	NP_001171944.1,NP_004500.3,NP_536349.2
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Sp110 nuclear body protein,Interferon-induced protein 41/75,Speckled 110 kDa,Transcriptional coactivator Sp110,SP110
Similar products	SP110, Sp110 nuclear body protein, Speckled 110 kDa, Interferon-induced protein 41/75, Transcriptional coactivator Sp110
Available
Manufacturer - Targets	SP110 (NP_004501, 271 a.a. ~ 380 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Bio Background	The nuclear body is a multiprotein complex that may have a role in the regulation of gene transcription. This gene is a member of the SP100/SP140 family of nuclear body proteins and encodes a leukocyte-specific nuclear body component. The protein can function as an activator of gene transcription and may serve as a nuclear hormone receptor coactivator. In addition, it has been suggested that the protein may play a role in ribosome biogenesis and in the induction of myeloid cell differentiation. Alternative splicing has been observed for this gene and three transcript variants, encoding distinct isoforms, have been identified.
Clonality	Monoclonal
Gene Name	SP110
Subtitle	Mouse monoclonal antibody raised against a partial recombinant SP110.
Reactivity	H
Antigen Source	Human: ~~ Positive
Formulation	Clear, colorless solution in phosphate buffered saline, pH 7.2 .
Dilution	IF WB: 1:500~1000 WB: 1:500~1000 E
Org Accession	NP_004501
Gene Description	SP110 nuclear body protein
Gene Summary	The nuclear body is a multiprotein complex that may have a role in the regulation of gene transcription. This gene is a member of the SP100/SP140 family of nuclear body proteins and encodes a leukocyte-specific nuclear body component. The protein can function as an activator of gene transcription and may serve as a nuclear hormone receptor coactivator. In addition, it has been suggested that the protein may play a role in ribosome biogenesis and in the induction of myeloid cell differentiation. Alternative splicing has been observed for this gene and three transcript variants, encoding distinct isoforms, have been identified. [provided by RefSeq
Antigen Type	Recombinant Protein

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ug

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Delivery expected until 1/1/2026

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