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SYNE1 Antibody (monoclonal) (M01)

SYNE1 Antibody (monoclonal) (M01)

Item no.	ABC-AT4121a
Manufacturer	Abcepta
Amount	50 ug
Category	Neuroscience Neural Lineage Markers Antibodies Western Blot ELISA Primary Antibodies Immunostaining
Type	Antibody Monoclonal
Format	Liquid
Applications	WB, ELISA
Clone	4C3
Specific against	Human (Homo sapiens)
Host	Mouse
Isotype	IgG3 Kappa
Citations	Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. Rose JE, et al. Mol Med, 2010 Jul-Aug. PMID 20379614.Meta-analysis of genome-wide association data of bipolar disorder and major depressive disorder. Liu Y, et al. Mol Psychiatry, 2010 Mar 30. PMID 20351715.Genome-wide association study of alcohol dependence implicates a region on chromosome 11. Edenberg HJ, et al. Alcohol Clin Exp Res, 2010 May. PMID 20201924.ESR1/SYNE1 polymorphism and invasive epithelial ovarian cancer risk: an Ovarian Cancer Association Consortium study. Doherty JA, et al. Cancer Epidemiol Biomarkers Prev, 2010 Jan. PMID 20056644.Mutation of SYNE-1, encoding an essential component of the nuclear lamina, is responsible for autosomal recessive arthrogryposis. Attali R, et al. Hum Mol Genet, 2009 Sep 15. PMID 19542096.
NCBI	NP_149062.1,NP_892006.3
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Nesprin-1,Enaptin,Myocyte nuclear envelope protein 1,Myne-1,Nuclear envelope spectrin repeat protein 1,Synaptic nuclear envelope protein 1,Syne-1,SYNE1,C6orf98,KIAA0796,KIAA1262,KIAA1756,MYNE1
Similar products	SYNE1, C6orf98, KIAA0796, KIAA1262, KIAA1756, MYNE1, Nesprin-1, Enaptin, Myocyte nuclear envelope protein 1, Nuclear envelope spectrin repeat protein 1, Synaptic nuclear envelope protein 1, Myne-1, Syne-1
Available
Manufacturer - Targets	SYNE1 (NP_892006, 1561 a.a. ~ 1670 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Bio Background	This gene encodes a spectrin repeat containing protein expressed in skeletal and smooth muscle, and peripheral blood lymphocytes, that localizes to the nuclear membrane. Mutations in this gene have been associated with autosomal recessive spinocerebellar ataxia 8, also referred to as autosomal recessive cerebellar ataxia type 1 or recessive ataxia of Beauce. Alternatively spliced transcript variants encoding different isoforms have been described.
Clonality	Monoclonal
Gene Name	SYNE1
Subtitle	Mouse monoclonal antibody raised against a partial recombinant SYNE1.
Reactivity	H
Antigen Source	Human: ~~ Positive
Formulation	Clear, colorless solution in phosphate buffered saline, pH 7.2 .
Dilution	WB: 1:500~1000 E
Org Accession	NP_892006
Gene Description	spectrin repeat containing, nuclear envelope 1
Gene Summary	This gene encodes a spectrin repeat containing protein expressed in skeletal and smooth muscle, and peripheral blood lymphocytes, that localizes to the nuclear membrane. Mutations in this gene have been associated with autosomal recessive spinocerebellar ataxia 8, also referred to as autosomal recessive cerebellar ataxia type 1 or recessive ataxia of Beauce. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq
Antigen Type	Recombinant Protein

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 50 ug

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Delivery expected until 1/1/2026

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