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SYT1 Antibody (monoclonal) (M01)

SYT1 Antibody (monoclonal) (M01)

Item no.	ABC-AT4125a
Manufacturer	Abcepta
Amount	100 ug
Category	Neuroscience Molecular Targets for Neuroscience Neural Signaling Antibodies Western Blot ELISA Immunofluorescence Primary Antibodies Immunostaining
Type	Antibody Monoclonal
Format	Liquid
Applications	WB, IF, ELISA
Clone	3A5
Specific against	Human (Homo sapiens)
Host	Mouse
Isotype	IgG2a Kappa
Citations	Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. Rose JE, et al. Mol Med, 2010 Jul-Aug. PMID 20379614.A meta-analysis of genome-wide data from five European isolates reveals an association of COL22A1, SYT1, and GABRR2 with serum creatinine level. Pattaro C, et al. BMC Med Genet, 2010 Mar 11. PMID 20222955.Cyclic AMP-mediated endocytosis of intestinal epithelial NHE3 requires binding to synaptotagmin 1. Musch MW, et al. Am J Physiol Gastrointest Liver Physiol, 2010 Feb. PMID 19926819.NMR characterization of copper and lipid interactions of the C2B domain of synaptotagmin I-relevance to the non-classical secretion of the human acidic fibroblast growth factor (hFGF-1). Kathir KM, et al. Biochim Biophys Acta, 2010 Feb. PMID 19835837.De novo STXBP1 mutations in mental retardation and nonsyndromic epilepsy. Hamdan FF, et al. Ann Neurol, 2009 Jun. PMID 19557857.
NCBI	NP_001129277.1,NP_001129278.1,NP_005630.1
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Synaptotagmin-1,Synaptotagmin I,SytI,p65,SYT1,SVP65,SYT
Similar products	SYT1, p65, SVP65, SYT, Synaptotagmin-1, Synaptotagmin I, SytI
Available
Manufacturer - Targets	SYT1 (AAH58917, 1 a.a. ~ 422 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Bio Background	The synaptotagmins are integral membrane proteins of synaptic vesicles thought to serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis. Calcium binding to synaptotagmin-1 participates in triggering neurotransmitter release at the synapse (Fernandez-Chacon et al., 2001 [PubMed 11242035]).
Clonality	Monoclonal
Gene Name	SYT1
Subtitle	Mouse monoclonal antibody raised against a full-length recombinant SYT1.
Reactivity	H
Antigen Source	Human: ~~ Positive
Formulation	Clear, colorless solution in phosphate buffered saline, pH 7.2 .
Dilution	IF WB: 1:500~1000 WB: 1:500~1000 E
Org Accession	AAH58917
Gene Description	synaptotagmin I
Gene Summary	The synaptotagmins are integral membrane proteins of synaptic vesicles thought to serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis. Calcium binding to synaptotagmin I participates in triggering neurotransmitter release at the synapse (Fernandez-Chacon et al., 2001 [PubMed 11242035]).[supplied by OMIM
Antigen Type	Recombinant Protein

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ug

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Delivery expected until 1/1/2026

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