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TDO2 Antibody (monoclonal) (M01)

TDO2 Antibody (monoclonal) (M01)

Item no.	ABC-AT4199a
Manufacturer	Abcepta
Amount	100 ug
Category	Antibodies Primary Antibodies
Type	Antibody Primary
Format	Clear, colorless solution in phosphate buffered saline, pH 7.2 .
Applications	ELISA
Clone	1C8
Specific against	other
Host	Mouse
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	TDO, Tryptophan 2, Tryptamin 2, 3-dioxygenase {ECO:0000255\|HAMAP-Rule:MF_03020}, TDO {ECO:0000255\|HAMAP-Rule:MF_03020}, 1131111 {ECO:0000255\|HAMAP-Rule:MF_03020}, Tryptophan oxygenase {ECO:0000255\|HAMAP-Rule:MF_03020}, TO {ECO:0000255\|HAMAP-Rule:MF_03020}, TRPO {ECO:0000255\|HAMAP-Rule:MF_03020}, Tryptophan pyrrolase {ECO:0000255\|HAMAP-Rule:MF_03020}, Tryptophanase {ECO:0000255\|HAMAP-Rule:MF_03020}, TDO2 {ECO:0000255\|HAMAP-Rule:MF_03020}
Available
Primary Accession	P48775
Antigen Type	Recombinant Protein
Application	E
Bio Background	Tryptophan 2, 3-dioxygenase (EC 1.13.11.11) plays a role in catalyzing the first and rat-limiting step in the kynurenine pathway, the major pathway of tryptophan metabolism.
Bio References	First genome-wide association scan on neurophysiological endophenotypes points to trans-regulation effects on SLC2A3 in dyslexic children. Roeske D, et al. Mol Psychiatry, 2009 Sep 29. PMID 19786962.Antimicrobial and immunoregulatory properties of human tryptophan 2, 3-dioxygenase. Schmidt SK, et al. Eur J Immunol, 2009 Oct. PMID 19637229.Two complex genotypes relevant to the kynurenine pathway and melanotropin function show association with schizophrenia and bipolar disorder. Miller CL, et al. Schizophr Res, 2009 Sep. PMID 19502010.Cooperative binding of L-trp to human tryptophan 2, 3-dioxygenase: resonance Raman spectroscopic analysis. Fukumura E, et al. J Biochem, 2009 Apr. PMID 19218188.A kinetic, spectroscopic, and redox study of human tryptophan 2, 3-dioxygenase. Basran J, et al. Biochemistry, 2008 Apr 22. PMID 18370401.
Clonality	Monoclonal
Gene ID	6999
Gene Name	TDO2 {ECO:0000255\|HAMAP-Rule:MF_03020}
Subtitle	Mouse monoclonal antibody raised against a partial recombinant TDO2.
Reactivity	H
Legend image 1	Detection limit for recombinant GST tagged TDO2 is approximately 10ng/ml as a capture antibody.
Type image 1	E
Other Accession	NM_005651
Isotype	IgG2a Kappa
Antigen Source	Human: ~~ Positive
Target/Specificity	TDO2 (NP_005642, 307 a.a. ~ 405 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
NCBI Accession	NP_005642.1
	Clone: 1C8
Org Accession	NP_005642
Gene Description	tryptophan 2, 3-dioxygenase
Gene Summary	Tryptophan 2, 3-dioxygenase (EC 1.13.11.11) plays a role in catalyzing the first and rat-limiting step in the kynurenine pathway, the major pathway of tryptophan metabolism.[supplied by OMIM

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ug

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