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TXNDC3 Antibody (monoclonal) (M01)

TXNDC3 Antibody (monoclonal) (M01)

Item no.	ABC-AT4416a
Manufacturer	Abcepta
Amount	100 ug
Category	Antibodies Primary Antibodies
Type	Antibody Primary
Format	Clear, colorless solution in phosphate buffered saline, pH 7.2 .
Applications	WB
Clone	1G5
Specific against	other
Host	Mouse
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	TXNDC3, NME8, SPTRX2, NM23-H8, Thioredoxin domain-containing protein 3, NME/NM23 family member 8, Spermatid-specific thioredoxin-2, Sptrx-2
Available
Primary Accession	Q8N427
Antigen Type	Recombinant Protein
Application	WB
Bio Background	This gene encodes a protein with an N-terminal thioredoxin domain and three C-terminal nucleoside diphosphate kinase (NDK) domains, but the NDK domains are thought to be catalytically inactive. The sea urchin ortholog of this gene encodes a component of sperm outer dynein arms, and the protein is implicated in ciliary function. Mutations in this gene are implicated in primary ciliary dyskinesia type 6.
Bio References	Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. Rose JE, et al. Mol Med, 2010 Jul-Aug. PMID 20379614.Field synopsis and synthesis of genetic association studies in osteoarthritis: the CUMAGAS-OSTEO information system. Zintzaras E, et al. Am J Epidemiol, 2010 Apr 15. PMID 20237151.Nme protein family evolutionary history, a vertebrate perspective. Desvignes T, et al. BMC Evol Biol, 2009 Oct 23. PMID 19852809.Association of single-nucleotide polymorphisms in RHOB and TXNDC3 with knee osteoarthritis susceptibility: two case-control studies in East Asian populations and a meta-analysis. Shi D, et al. Arthritis Res Ther, 2008. PMID 18471322.A common variant in combination with a nonsense mutation in a member of the thioredoxin family causes primary ciliary dyskinesia. Duriez B, et al. Proc Natl Acad Sci U S A, 2007 Feb 27. PMID 17360648.
Clonality	Monoclonal
Gene ID	51314
Gene Name	NME8
Subtitle	Mouse monoclonal antibody raised against a partial recombinant TXNDC3.
Reactivity	H
Legend image 1	Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (32.01 KDa) .
Type image 1	WB
Dilution image 1	1:500~1000
Legend image 2	TXNDC3 monoclonal antibody (M01), clone 1G5. Western Blot analysis of TXNDC3 expression in Jurkat ( (Cat # AT4416a )
Type image 2	WB
Dilution image 2	1:500~1000
Other Accession	NM_016616
Isotype	IgG2a Kappa
Antigen Source	Human: ~~ Positive
Target/Specificity	TXNDC3 (NP_057700, 530 a.a. ~ 586 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
NCBI Accession	NP_057700.3
	Clone: 1G5
Org Accession	NP_057700
Gene Description	thioredoxin domain containing 3 (spermatozoa)
Gene Summary	TXNDC3 encodes a group II thioredoxin protein, composed of a thioredoxin domain and 3 NDP kinase domains, with testis-specific expression.[supplied by OMIM

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ug

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