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VIM Antibody (monoclonal) (M01)

VIM Antibody (monoclonal) (M01)

Item no.	ABC-AT4513a
Manufacturer	Abcepta
Amount	100 ug
Category	Neuroscience Neural Lineage Markers Molecular Targets for Neuroscience Neural Development Antibodies Cell Biology Cytoskeleton Immunoprecipitation Western Blot Immunofluorescence Primary Antibodies Intermediate filaments Stem Cell Markers
Type	Antibody Monoclonal
Format	Liquid
Applications	WB, IF, IP
Clone	3000000000
Specific against	Human (Homo sapiens)
Host	Mouse
Isotype	IgG2a Kappa
Citations	Aberrant expression of vimentin correlates with dedifferentiation and poor prognosis in patients with intrahepatic cholangiocarcinoma. Korita PV, et al. Anticancer Res, 2010 Jun. PMID 20651380.Proteome analysis of the thalamus and cerebrospinal fluid reveals glycolysis dysfunction and potential biomarkers candidates for schizophrenia. Martins-de-Souza D, et al. J Psychiatr Res, 2010 May 14. PMID 20471030.Association study of 182 candidate genes in anorexia nervosa. Pinheiro AP, et al. Am J Med Genet B Neuropsychiatr Genet, 2010 Jul. PMID 20468064.Divalent cations crosslink vimentin intermediate filament tail domains to regulate network mechanics. Lin YC, et al. J Mol Biol, 2010 Jun 18. PMID 20447406.Diagnostic value and implications of vimentin expression in normal, reactive and neoplastic endocervical epithelium. Stewart CJ, et al. Pathology, 2010 Apr. PMID 20350213.
NCBI	NP_003371.2
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Vimentin,VIM
Similar products	Vimentin, VIM
Available
Manufacturer - Targets	VIM (AAH30573, 41 a.a. ~ 140 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Bio Background	This gene encodes a member of the intermediate filament family. Intermediate filamentents, along with microtubules and actin microfilaments, make up the cytoskeleton. The protein encoded by this gene is responsible for maintaining cell shape, integrity of the cytoplasm, and stabilizing cytoskeletal interactions. It is also involved in the immune response, and controls the transport of low-density lipoprotein (LDL)-derived cholesterol from a lysosome to the site of esterification. It functions as an organizer of a number of critical proteins involved in attachment, migration, and cell signaling. Mutations in this gene causes a dominant, pulverulent cataract.
Clonality	Monoclonal
Gene Name	VIM
Subtitle	Mouse monoclonal antibody raised against a partial recombinant VIM.
Reactivity	H
Antigen Source	Human: ~~ Positive
Formulation	Clear, colorless solution in phosphate buffered saline, pH 7.2 .
Dilution	IF IF IF IP WB: 1:500~1000
Org Accession	AAH30573
Gene Description	vimentin
Gene Summary	This gene encodes a member of the intermediate filament family. Intermediate filamentents, along with microtubules and actin microfilaments, make up the cytoskeleton. The protein encoded by this gene is responsible for maintaining cell shape, integrity of the cytoplasm, and stabilizing cytoskeletal interactions. It is also involved in the immune response, and controls the transport of low-density lipoprotein (LDL)-derived cholesterol from a lysosome to the site of esterification. It functions as an organizer of a number of critical proteins involved in attachment, migration, and cell signaling. Mutations in this gene causes a dominant, pulverulent cataract
Antigen Type	Recombinant Protein

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ug

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Delivery expected until 1/1/2026

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