PE-Cyanine7 Anti-Human CD45 (2D1) Antibody

P08575

human CD45, one of the most abundant hematopoietic markers and one that is expressed on all leukocytes (the Leukocyte Common Antigen, LCA). CD45 is a protein tyrosine phosphatase existing in several isoforms, each being generated and expressed in cell-specific patterns. With its broad cell distribution, CD45 is critical for many leukocyte functions, regulating signal transduction and cell activation associated with the T cell receptor, B cell receptor, and IL-2 receptor. Other forms of CD45, with restricted cellular expression, include CD45R (B220), CD45RA, CD45RB, and CD45RO.

PTPRC (HGNC:9666)

Human PBMCs were stained with 5 uL (0.25 ug) PE-Cyanine7 Anti-Human CD45 (ATB10449) (right panel) or 0.25 ug PE-Cyanine7 Mouse IgG1 isotype control (left panel).

Mouse IgG1, kappa