Comparison

STAT3 Antibody

Item no. ABC-AW5072-U100
Manufacturer Abcepta
Amount 100 ul
Category
Type Antibody Primary
Applications WB
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host Mouse
Isotype IgG2a Kappa
Citations Akira S.,et al.Cell 77:63-71(1994).
Della Pietra L.,et al.Gene 213:119-124(1998).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Della Pietra L.,et al.Submitted (OCT-1997) to the EMBL/GenBank/DDBJ databases.
Zhang X.,et al.Science 267:1990-1994(1995).
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias Signal transducer and activator of transcription 3,Acute-phase response factor,STAT3,APRF
Similar products STAT3, APRF, Signal transducer and activator of transcription 3, Acute-phase response factor
Available
Manufacturer - Category
Primary Antibodies; Stem Cells; Viral process; Host-virus interaction; Chemokine signaling; Inflammation mediated by chemokine and cytokine signaling; Interleukin signaling; JAK-STAT signaling; Jak-STAT signaling KEGG
Manufacturer - Targets
This STAT3 antibody is generated from a mouse immunized with a recombinant protein from human.
Bio Background
Signal transducer and transcription activator that mediates cellular responses to interleukins, KITLG/SCF and other growth factors. May mediate cellular responses to activated FGFR1, FGFR2, FGFR3 and FGFR4. Binds to the interleukin-6 (IL-6)- responsive elements identified in the promoters of various acute- phase protein genes. Activated by IL31 through IL31RA. Cytoplasmic STAT3 represses macroautophagy by inhibiting EIF2AK2/PKR activity. Plays an important role in host defense in methicillin-resistant S.aureus lung infection by regulating the expression of the antimicrobial lectin REG3G (By similarity).
Clonality
Monoclonal
Gene Name
STAT3 {ECO:0000303|PubMed:9630560, ECO:0000312|HGNC:HGNC:11364}
Subtitle
Purified Mouse Monoclonal Antibody (Mab)
Reactivity
H, M
Predicted Reactivity
Pig, Rat
Calculated Molecular Weight
88068
Antigen Source
HUMAN
Antigen Region
1-280
Formulation
Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.
Dilution
WB: 1:1000
Antigen Type
Recombinant Protein

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 100 ul
Available: In stock
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