Phospho-ErbB2(Y1112) Antibody

Item no.	ABC-AW5151-U100
Manufacturer	Abcepta
Amount	100 ul
Category	Oncology Neuroscience Neural Adhesion Molecules Antibodies By Cell Type Blastoma Carcinoma Glioma Hematology Leukemia Lymphoma Myeloma Melanoma Sarcoma Western Blot Primary Antibodies By Organ Lung Cancer Bladder Cancer Colorectal Cancer Breast Cancer
Type	Antibody Primary
Applications	WB
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Citations	Stephens, P., et al., Nature 431(7008):525-526 (2004). Wang, S.C., et al., Cancer Cell 6(3):251-261 (2004). Menendez, J.A., et al., Proc. Natl. Acad. Sci. U.S.A. 101(29):10715-10720 (2004). M, et al., Anticancer Res. 24(4):2219-2224 (2004). Contreras, D.N., et al., Clin. Appl. Thromb. Hemost. 10(3):271-276 (2004).
NCBI	NP_001005862.1,NP_004439.2
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Receptor tyrosine-protein kinase erbB-2 [Precursor],p185erbB2,C-erbB-2,NEU proto-oncogene,Tyrosine kinase-type cell surface receptor HER2,MLN 19,ERBB2,HER2,NEU,NGL
Similar products	ERBB2, p185erbB2, Receptor tyrosine-protein kinase erbB-2 [Precursor], C-erbB-2, NEU proto-oncogene, Tyrosine kinase-type cell surface receptor HER2, MLN 19, HER2, NEU, NGL
Available
Manufacturer - Category	Primary Antibodies; Antibody Collections; Phospho Antibodies; Anti-Kinome Antibodies
Manufacturer - Targets	This ErbB2 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Y1112 of human ErbB2.
Bio Background	ErbB2 is a member of the epidermal growth factor (EGF) receptor family of receptor tyrosine kinases. This protein has no ligand binding domain of its own and therefore cannot bind growth factors. However, it does bind tightly to other ligand-bound EGF receptor family members to form a heterodimer, stabilizing ligand binding and enhancing kinase-mediated activation of downstream signalling pathways, such as those involving mitogen-activated protein kinase and phosphatidylinositol-3 kinase. Amplification and/or overexpression of this gene has been reported in numerous cancers, including breast and ovarian tumors.
Clonality	Polyclonal
Gene Name	ERBB2
Subtitle	Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Calculated Molecular Weight	137910
Antigen Source	HUMAN
Antigen Region	1100-1118
Formulation	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Dilution	WB: 1:4000 WB: 1:500
Antigen Type	Synthetic Peptide

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ul

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Delivery expected until 1/1/2026

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