HDAC2 Antibody (C-term)

Item no.	ABC-AW5398-U100
Manufacturer	Abcepta
Amount	100 ul
Category	Oncology Neuroscience Neural Epigenetics Antibodies By Cell Type Carcinoma Hematology Lymphoma Melanoma Sarcoma Immunohistochemistry Western Blot Immunofluorescence Primary Antibodies
Type	Antibody Primary
Applications	WB, IF, IHC-P
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host	Rabbit
Isotype	IgG
Citations	Choi, Y.B., et al., J. Biol. Chem. 279(49):50930-50941 (2004). Zhu, P., et al., Cancer Cell 5(5):455-463 (2004). Longworth, M.S., et al., J. Virol. 78(7):3533-3541 (2004). Lu, Y., et al., J. Biol. Chem. 278(48):47792-47802 (2003). Verdin, E., et al., Trends Genet. 19(5):286-293 (2003).
NCBI	NP_001518.3
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Histone deacetylase 2,HD2,HDAC2
Similar products	HDAC2, HD2, Histone deacetylase 2
Available
Manufacturer - Category	Primary Antibodies; Stem Cells; Anti-Wnt-Pathway (plus Lgr5) Antibodies; SARS druggable targets; SARS CoV2 PPIs; Poly(A) RNA binding
Manufacturer - Targets	This HDAC2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 456-488 amino acids from the C-terminal region of human HDAC2.
Bio Background	Histone deacetylase 2 (HDAC2), or transcriptional regulator homolog RPD3 L1, is highly homologous to the yeast transcription factor RPD3 (reduced potassium dependency 3) gene. As in yeast, human HDA2 is likely to be involved in regulating chromatin structure during transcription. It has been implicated to associate with YY1, a mammalian zinc-finger transcription factor, which negatively regulates transcription by tethering RPD3 to DNA as a cofactor. This process is highly conserved from yeast to human.
Clonality	Polyclonal
Gene Name	HDAC2 {ECO:0000303\|PubMed:10545197, ECO:0000312\|HGNC:HGNC:4853}
Subtitle	Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H, M
Calculated Molecular Weight	55364
Antigen Source	HUMAN
Antigen Region	456-488
Formulation	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Dilution	IF: 1:10~50 IF: 1:10~50 WB: 1:1000 IHC-P: 1:10~50
Antigen Type	Synthetic Peptide

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ul

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