Comparison

(Mouse) Suz12 Antibody (Center)

Item no. ABC-AW5499-U100
Manufacturer Abcepta
Amount 100 ul
Category
Type Antibody Primary
Applications WB
Specific against other
Host Rabbit
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Similar products Suz12, Suppressor of zeste 12 protein homolog, Polycomb protein Suz12, D11Ertd530e, Kiaa0160
Available
Primary Accession
Q80U70
Antigen Type
Synthetic Peptide
Application
WB
Bio Background
Polycomb group (PcG) protein. Component of the PRC2/EED- EZH2 complex, which methylates 'Lys-9' (H3K9me) and 'Lys-27' (H3K27me) of histone H3, leading to transcriptional repression of the affected target gene. The PRC2/EED-EZH2 complex may also serve as a recruiting platform for DNA methyltransferases, thereby linking two epigenetic repression systems (By similarity). Genes repressed by the PRC2/EED-EZH2 complex include HOXA7, HOXB6 and HOXC8.
Bio References
Okazaki N., et al.DNA Res. 10:35-48(2003).
Church D.M., et al.PLoS Biol. 7:E1000112-E1000112(2009).
Pasini D., et al.EMBO J. 23:4061-4071(2004).
Umlauf D., et al.Nat. Genet. 36:1296-1300(2004).
Kuzmichev A., et al.Proc. Natl. Acad. Sci. U.S.A. 102:1859-1864(2005).
Clonality
Polyclonal
Gene ID
52615
Gene Name
Suz12
Subtitle
Purified Rabbit Polyclonal Antibody (Pab)
Reactivity
H, M
Legend image 1
All lanes : Anti-Suz12 Antibody (Center) at 1:1000 dilution
Lane 1: F9 whole cell lysates
Lane 2: SW480 whole cell lysates

Lysates/proteins at 20 µg per lane.

Secondary
Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution

Predicted band size : 83 kDa

Blocking/Dilution buffer: 5% NFDM/TBST.
Type image 1
WB
Dilution image 1
1:1000
Isotype
Rabbit Ig
Calculated MW
83026
Antigen Region
496-530
Antigen Source
HUMAN
Target/Specificity
This Mouse Suz12 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 496-530 amino acids from the Central region of Mouse Suz12.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 100 ul
Available: In stock
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