Comparison

ACE2 Recombinant Antibody AE00343 European Partner

Item no. AE00343-1mg-B
Manufacturer Aeonian Biotech
Amount 1mg
Category
Type Antibody Monoclonal, recombinant
Applications IHC
Clone AE919R
Specific against Human (Homo sapiens)
Host Rabbit
Isotype IgG kappa
Formula 1mg igG/ml in PBS with 0.05% azide upon quotation
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Alias Angiotensin converting enzyme 2; Angiotensin-converting enzyme homolog; Angiotensin-converting enzyme-related carboxypeptidase; ACE-related carboxypeptidase; Coronavirus receptor; Metalloprotease MPROT15; ACE2; ACEH
Available
Description
Specific, and tissue microarray-validated rabbit recombinant antibody clone AE919R to human ACE2
Principle name
ACE2
epitope
aa 705-805
immunogen
Recombinant fragment around aa 705-805 of human ACE2 (exact sequence is proprietary)
purification method
By Protein A from bioreactor concentrate
Cell. Localization
cell surface, secreted
Positive controls
duodenum, endothelial cells, gallbladder, kidney, ovary, renal carcinoma, small intestine, testis
RRID
AB_2916347
IHC comments
AE00343 to ACE2 was successfully used to stain epithelial surface of human duodenum sections, proximal tubuli in human kidney sections, and Leydig cells plus spermatocytes in human testis sections. Recommended concentration: 1-3ug/ml
Tissue Microarray Validation (Normal tissue)
strong positive: cardial endothelium; corpus luteum; duodenum mucosa; endothelial cells; gallbladder; ileum mucosa; renal proximal tubuli; testis | weak to moderate: adrenal gland; appendix mucosa; appendix muscular wall; colon; epididymis; fallopian tube; heart muscle; myometrium; pancreas; placenta; rectum mucosa; renal medula; seminal vesicles; stomach; thyroid gland | no staining at all: adipose; aorta, media; bone marrow; breast; cerebellum; cerebrum; duodenum Brunner gland; endocervix; endometrium; epidermis; esophageal squamous epithelium; liver; lung; lymph node; ovarian stroma;
Tissue Microarray Validation (Cancer tissue)
strong positive: adrenocortical adenoma; capillaries in ACE2-negative neuroendocrine tumour; capillaries in ACE2-negative thyroid medullary carcinoma; clear cell renal cell carcinoma; colorectal adenocarcinoma; esophageal adenocarcinoma; gastric adenocarcinoma; hepatic cholangiocellular carcinoma; papillary renal cell carcinoma | weak to moderate: cholangiocarcinoma; prostate adenocarcinomas; urothelial carcinoma | no staining at all: breast cancer no special type; chromophobe renal cell carcinoma; high-grade serous carcinoma; renal oncocytoma; seminoma
Expiration
Integrity warranted for 24 months after purchase when handled and stored according to instructions, see below.
Storage
Avoid repeated freeze/thaw cycles. For long term storage, keep small aliquots at -20°C or -80°C and keep one aliquot at 4°C for daily experimentations. Azide will preserve antibody at 4°C for 6-12 months, when kept away from direct sun light.
Warranty
This product is only warranted for the specifications as described in this product sheet and only when the product is handled and stored according to instructions. User should validate this antibody in the application and tissue/cell type as required, after confirmation of integrity upon receipt is obtained by reproducing the performance as described below. Should such confirmation not be attempted, any warranty is void. In case of non-conformance, user needs to contact us immediately for replacement or refund.
Liability
This product is for in vitro research use only. Any other applications, such as diagnostics or therapeutics, or in vivo experiments, and the validation of this product therein, are solely at the responsibility of the buyer/user.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 1mg
Available: In stock
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