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Melan A Recombinant Antibody AE00375

Melan A Recombinant Antibody AE00375

Item no.	AE00375-0.2mg-A
Manufacturer	Aeonian Biotech
Amount	0.2mg
Category	Antibodies Primary Antibodies
Type	Antibody Monoclonal, recombinant
Applications	IHC
Clone	AE900M
Specific against	Human (Homo sapiens)
Host	Mouse
Isotype	IgG2a kappa
Formula	0.2 mg IgG/ml in PBS with 0.05% BSA & 0.05% azide.
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Antigen LB39-AA; Antigen SK29-AA; Melanoma antigen recognized by T-cells 1; Melan-A; MelanA; Melan A; MART1; MART-1; MLANA
Available
Description	Specific, and tissue microarray-validated mouse recombinant antibody clone AE900M to human Melan A
Principle name	Melan A
immunogen	Recombinant full length human Melan A protein
purification method	By Protein A from bioreactor concentrate
Cell. Localization	Endoplasmatic Reticulum, Golgi, melanosome
Positive controls	melanoma, skin
RRID	AB_2921276
IHC comments	AE00375 to Melan A was successfully used to stain melanocytes in healthy skin, non-neoplastic melanocytes in Melan A-negative basal cell carcinoma, and tumour cells in melanoma sections. Recommended concentration: 1-3 μg/ml
Tissue Microarray Validation (Normal tissue)	strong positive: skin \| weak to moderate: \| no staining at all: adipose; adrenal gland; aorta media; appendix mucosa; appendix muscular wall; bone marrow; breast; bronchus mucosa; cerebellum; cerebrum; colon mucosa; colon muscular wall; duodenum Brunner gland; duodenum mucosa; ectocervix; endocervix; endometrium; epididymis; esophagus squamous epithelium; fallopian tube; gallbladder; heart muscle; ileum mucosa; kidney; liver; lung; myometrium; ovarian stroma; pancreas; parathyroid gland; parotid gland; pituitary gland; placenta; pregnant uterus; prostate; rectum mucosa; seminal vesicle; sinus paranasalis; skeletal muscle; spleen; stomach; testis; thymus ; thyroid gland; tonsil; urinary bladder muscular wall; urothelium
Tissue Microarray Validation (Cancer tissue)	strong positive: melanoma \| weak to moderate: \| no staining at all: adrenocortical adenoma; adrenocortical carcinoma; basal cell carcinoma; clear cell renal cell carcinoma; colorectal adenocarcinoma; endometrioid ovarian carcinoma; high-grade serous carcinoma; pancreas ductal adenocarcinoma; pharynx squamous cell carcinoma; prostate adenocarcinoma; renal oncocytoma; skin squamous cell carcinoma; urothelial carcinoma
Expiration	Integrity warranted for 24 months after purchase when handled and stored according to instructions, see below.
Storage	Avoid repeated freeze/thaw cycles. For long term storage, keep small aliquots at -20°C or -80°C and keep one aliquot at 4°C for daily experimentations. Azide will preserve antibody at 4°C for 6-12 months, when kept away from direct sun light.
Warranty	This product is only warranted for the specifications as described in this product sheet and only when the product is handled and stored according to instructions. User should validate this antibody in the application and tissue/cell type as required, after confirmation of integrity upon receipt is obtained by reproducing the performance as described below. Should such confirmation not be attempted, any warranty is void. In case of non-conformance, user needs to contact us immediately for replacement or refund.
Liability	This product is for in vitro research use only. Any other applications, such as diagnostics or therapeutics, or in vivo experiments, and the validation of this product therein, are solely at the responsibility of the buyer/user.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

AE00375-0.2mg-A-datasheet.pdf

AE00375-0.2mg-A-safety-datasheet.pdf