C Reactive Protein (CRP) polyclonal (*HRP Labeled)

HRP conjugated goat polyclonal antibody to human C reactive protein (CRP)

Purified CRP from human pleural fluid

Protein G affinity purified

C-reactive protein (CRP) is an acute phase protein that is comprised of five identical 23kDa subunits. The protein increases rapidly in response to inflammation, trauma and infection, and drops to normal level when the conditions no longer present. CRP plays a role in innate immunity by binding to phosphachlolin on the surface of damaged cells or certain microbes, and activating the C1q complex in complement system. CRP is primarily produced by hepatocytes under the stimulation by inflammatory cytokines including IL-6 and TNF-alpha. Elevated CRP level is implicated with bacterial infection, autoimmune diseases, trauma and post-surgical complications. Study has shown that people with higher CRP baseline have a higher disposition to develop cardiovascular diseases such as heart attack and stroke.

ELISA: In combination with CRP capture antibody [Clone 63F4, Cat No: MO-M40023A], this HRP conjugated antibody can be used as tracer in Sandwich ELISA for CRP detection.

Store at -20C