BCL-2

Item no.	ANOG-AI70003A-0.1mg
Manufacturer	Anogen
Amount	0.1mg
Category	Oncology Antibodies By Cell Type Blastoma Carcinoma Hematology Leukemia Lymphoma Myeloma Cell Biology Cell Status Apoptosis ELISA Autophagy Primary Antibodies By Organ Lung Cancer Skin Cancer Colorectal Cancer Breast Cancer Testicular & Prostate Cancer
Type	Antibody Polyclonal
Format	Purified
Applications	ELISA
Specific against	Human (Homo sapiens)
Host	Rabbit
Protein Family	Signal Transduction
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	BCL-2
Available
Description	Rabbit anti- B cell lymphoma factor 2 (Bcl-2) polyclonal antibody
Target Protein	Bcl-2
Immunogen	A synthetic peptide (AGRTGYDNREIVMKY) derived from human Bcl-2, conjugated with KLH for immunization
Specificity	This antibody recognizes the synthetic Bcl-2 peptide.
Purification	Protein G affinity purified
Species Reactivity	Human, others not tested
Background	Bcl2 is a 25kDa inner mitochondrial membrane protein with anti-apoptotic function. It is believed that Bcl-2 suppresses apoptosis by inhibiting mitochondrial cytochrome C release, blocking caspase cascade and regulating mitochondrial calcium homeostasis. Bcl-2 is identified from the study of B-cell lymphoma. About 90% of follicular lymphoma is caused by Bcl-2 over-expression resulted from the translocation of Bcl-2 gene from chromosome 18 to the immunoglobulin heavy chain enhancer on chromosome 14. Bcl-2 is also involved with other malignancies such as melanoma, breast cancer, prostate cancer and lung cancer.
Formulation	Lyophilized in pH 7.4, 0.01M PBS.
Reconstitution	Double distilled water is recommended to adjust the final concentration to 1.00mg/mL.
Application info	ELISA: React with the synthetic Bcl-2 peptide coated on ELISA plate. Other applications have not been evaluated.
Research Area	Life science research, Oncology, apoptosis signalling pathway
Storage	Store at -20C

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 0.1mg

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Delivery expected until 9/18/2025

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