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Twik Related Potassium Channel 1 Protein (TREK-1)

Twik Related Potassium Channel 1 Protein (TREK-1)

Item no.	ANOG-AI80006A-0.5mg
Manufacturer	Anogen
Amount	0.5mg
Category	Antibodies ELISA Cardiovascular Research Ischemia & Reperfusion Injury Primary Antibodies
Type	Antibody Polyclonal
Format	Purified
Applications	ELISA
Specific against	Human (Homo sapiens)
Host	Rabbit
Protein Family	Signal Transduction
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	TREK-1
Available
Description	Rabbit anti-human Twik-related potassium channel 1 protein (TREK-1) polyclonal antibody
Target Protein	TREK-1
Immunogen	A synthetic peptide (SASRERPGYTA) derived from the amino sequence 4-14 of human TREK-1, conjugated with KLH for immunization.
Specificity	This antibody reacts with the 47kDa TREK-1 in Jurkat cell extract.
Purification	Protein G affinity purified
Species Reactivity	Human and other species with consensus TREK-1 peptide (SASRERPGYTA)
Background	TWIK-related potassium channel 1(TREK-1), also known as K2P2.1, is a two pore domain gated potassium channel that is involved with pain reception. TREK-1 is highly expressed in small sensory neurons and is extensively colocalized with TRPV1. TREK-1 is sensitive to noxious stimuli including extracellular pH, temperature, mechanical force, osmotic pressure and other stimuli. TREK-1 is one of the targets for pain mediator and anaesthesia drug.
Formulation	Lyophilized in pH 7.4, 0.01M PBS.
Reconstitution	Double distilled water is recommended to adjust the final concentration to 1.00mg/mL.
Application info	ELISA: The antibody (1:500, 000 diluted) can detect the TREK-1 peptide coated on ELISA plate at 100ng/well. Western blot: Dilute approx. 1:3, 000 for using in Western blot to detect the 47kDa TREK-1 in Jurkat cell extract.
Research Area	Life science research, stem cell factor signalling, cancer research
Storage	Store at -20C

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 0.5mg

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Delivery expected until 9/18/2025

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