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mAb anti-Human IL-1beta

mAb anti-Human IL-1beta

Item no.	ANOG-MO-C40029H-0.1mg
Manufacturer	Anogen
Amount	0.1mg
Category	Neuroscience Neuroinflammation Metabolism Cholesterol & Lipid Metabolism Antibodies Cell Biology Cell Movement Cell Adhesion Cell Culture Cytokines ELISA Primary Antibodies
Type	Antibody Monoclonal
Applications	ELISA
Clone	464
Specific against	Human (Homo sapiens)
Host	Mouse
Isotype	IgM kappa
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Available
Description	Mouse monoclonal antibody to human Interleukin-1 beta (IL-1beta)
Target Protein	Human IL-1beta
Immunogen	Purified recombinant human IL-1beta
Specificity	Reactive with natural and recombinant human IL-1beta
Purification	Protein G affinity purified
Cross Reactivity	Does not show any cross reaction with recombinant human IL-1alpha, recombinant murine IL-1alpha or IL-1beta.
Myeloma	Sp2/0-Ag14
Light chain	Kappa
Background	Interleukin 1beta (IL-1beta) shares the IL-1 receptor with other cytokines in IL-1 family. It is primarily produced by activated macrophage as a proprotein, which is cleaved by caspase I to become active. Like IL-1alpha, IL-1beta is an important mediator of innate immunity. IL-1beta stimulates lymphocyte proliferation and the production of TNF-alpha, IL-6 and IL-8. IL-1beta and TNF-alpha can synergically act at NFkB and mitogen kinases including JNKs and p38 MARKs, thus leading to the selective expression of genes for immunity and inflammation.
Formulation	Lyophilized from a solution in 0.01M PBS, pH 7.2.
Reconstitution	Double distillated water is recommended to reconstitute the antibody.
Research Area	Cytokines and Growth Factors
Storage	Store at -20oC

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 0.1mg

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Delivery expected until 9/18/2025

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