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Interleukin-16 (IL-16)

Interleukin-16 (IL-16)

Item no.	ANOG-MO-C40089K
Manufacturer	Anogen
Amount	0.5mg
Category	Oncology Neuroscience Neuroinflammation Metabolism Diabetes Glucose Homeostasis Aging & Neurological Disorders Antibodies Western Blot ELISA Primary Antibodies By Organ Colorectal Cancer Heart & Blood Cancer
Type	Antibody Monoclonal
Format	Aff. Pur
Applications	WB, ELISA
Clone	398
Specific against	Human (Homo sapiens)
Host	Mouse
Isotype	IgG1 kappa
Protein Family	Cytokine, Growth Factors
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Similar products	IL-16
Available
Description	Mouse monoclonal antibody to human interleukin 16 (IL-16)
Target Protein	Human IL-16
Immunogen	Purified recombinant human IL-16
Specificity	Reactive with natural and recombinant human IL-16
Purification	Protein G affinity purified
Species Reactivity	Human, other species not tested
Cross Reactivity	mAb 398 exhibits no detectable cross-reaction with human serum albumin, bovine serum albumin and other human cytokines or growth factors tested, such as IL-1beta, IL-8, IL-7 MCAF, TGF-beta1, EGF, bFGF, GM-CSF, M-CSF, TNF-alpha.
Myeloma	Sp2/0-Ag14
Background	Interleukin 16 (IL-16) is a pleiotropic cytokine, possessing immunomodulation function to allergic inflammatory diseases such as Crohn's disease and ulcerative colitis. IL-16 utilizes CD4 as its primary receptor. IL-16 is a chemo-attractant to CD4+ T helper 1 cells. To CD4+ T helper 2 cells, IL-16 has an inhibitory effect on the antigen-mediated CD3/T cell receptor activation. IL16 has been shown to suppress HIV infection in lymphocytes and monocytes.
Formulation	Lyophilized from a solution in 0.01M PBS, pH 7.2
Reconstitution	Double distilled water is recommended to adjust the final concentration to 1.00mg/mL.
Application info	ELISA: This antibody can be used as a capture antibody in sandwich ELISA applications for human IL-16 detection in combination with a monoclonal tracer/detection antibody (HRP-conjugated, Cat. No.: MO-C40089T). Suggested Capture Coating Dose: 0.3ug/well; Substrate: TMB. If the above suggested conditions are followed, approximately 20pg/mL of IL-16 in serum/plasma or 15 pg/mL of IL-16 in cell medium/urine can be detected with an assay range of 0-1000 pg/mL. Western Blot
Research Area	Cytokine
Storage	Store at -20C

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 0.5mg

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Delivery expected until 12/18/2025

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