Comparison

mAb anti-human GM-CSF

Item no. ANOG-MO-C40090D-0.1mg
Manufacturer Anogen
Amount 0.1mg
Category
Type Antibody Monoclonal
Applications WB, ELISA, Blocking
Clone 429
Specific against Human (Homo sapiens)
Host Mouse
Isotype IgG1 kappa
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Available
Description
Mouse monoclonal antibody to human granulocyte macrophage colony stimulating factor (GM-CSF)
Target Protein
Human GM-CSF
Immunogen
Purified recombinant human GM-CSF
Specificity
Reacts with natural and recombinant human GM-CSF
Purification
Protein G affinity purified
Cross Reactivity
Does not show any cross reaction with other human cytokines or growth factors tested such as M-CSF, G-CSFR, IL-8, IL-16, IL-1beta, TGF-beta1 and TNF-alpha.
Myeloma
Sp2/0-Ag14
Light chain
Kappa
Background
GM-CSF is an extracellular homodimer polyprotein, functioning as a hematopoietic growth factor and immune modulator. It can be produced and act upon a variety of cell types, including T-lymphocytes, B-lymphocytes, monocytes/macrophages, endothelial cells, fibroblasts, stromal cells, mesothelial cells, keratinocytes, osteoblasts, uterine epithelial cells, synoviocytes, mast cells and various solid tumors. GM-CSF stimulates stem cells to produce granulocytes and monocytes to cope with infection. Recombinant GM-CSF has been applied to boost white blood cell in cancer patients after chemotherapy and may also be useful as an immune tonic for anemia and AIDS patients.
Formulation
Lyophilized from a solution in 0.01M PBS, pH 7.2.
Reconstitution
Double distillated water is recommended to reconstitute the antibody.
Research Area
Cytokines and Growth Factors
Storage
Store at -20oC

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 0.1mg
Available: In stock
available

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