Hepatitis C Virus (HCV) NS-3

Mouse monoclonal antibody to human hepatitis virus C (HCV) non-structural protein NS-3

A highly antigenic polypeptide consisting of essential sequences of at least 60 residues in length, which were selected from genes encoding the NS-3 region of a Chinese HCV strains

Protein G affinity purified

No cross reaction with HCV polyprotein core region and other non-structural regions.

Hepatitis C virus (HCV) causes chronic hepatitis and liver cirrhosis in human through blood and body fluid transmission. HCV has a positive sense single RNA genome enclosed in the nucleocapsid made of core protein (capsid protein). The nucleocapsid is covered by an envelope made of lipoproteins (E1 and E2). The 9.6 kb HCV genome has a single open-reading frame, which is to be translated into a single polyprotein. HCV viral proteins are produced after processing the polyprotein. Genes for core protein and envelop proteins are located adjacently at the 5’-end of HCV genome, followed by genes for non-structural proteins including NS2, NS3, NS4A, NS4B, NS5, NS5A and NS5B.

Double distillated water is recommended to adjust the final concentration to 1.00mg/mL.

Virology