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H. pylori (HP) cytotoxin associated gene A protein (CagA)

H. pylori (HP) cytotoxin associated gene A protein (CagA)

Item no.	ANOG-MO-I40020C
Manufacturer	Anogen
Amount	0.5mg
Category	Oncology Antibodies ELISA Primary Antibodies By Organ Heart & Blood Cancer
Type	Antibody Monoclonal
Format	Aff. Pur
Applications	ELISA
Clone	5C6
Specific against	Human (Homo sapiens)
Host	Mouse
Isotype	IgG1 kappa
Protein Family	Infectious Agents
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Similar products	HP (CagA)
Available
Description	Mouse monoclonal antibody (mAb) against the H. pylori cytotoxin associated gene A protein (CagA)
Target Protein	H. pylori cytotoxin associated gene A protein (CagA)
Immunogen	A highly immunogenic 32kD CagA fragment, recombinant
Specificity	The mAb reacts with H. pylori CagA.
Purification	Protein G affinity purified
Species Reactivity	Human
Cross Reactivity	Cross-reaction with other proteins has not been identified.
Myeloma	Sp2/0-Ag14
Background	Helicobacter pylori (H. pylori), a spiral rod shaped gram-negative bacterium, is frequently found in the stomach. In infected populations, 10-20% may develop gastritis and gastric ulcer and 1-2% may develop cancer. The genome of H. pylori isolates from carriers with symptoms contains a 40kb pathogenicity island encoding H. pylori cytotoxin, cytotoxin associated gene A protein (CagA) and other virulence associated factors. CagA is used as a biomarker for virulent H. pylori strains.
Formulation	Lyophilized from a solution in 0.01M PBS, pH 7.0
Reconstitution	Double distillated water is recommended to adjust the final concentration to 1.00mg/mL.
Application info	ELISA: Clone 5C6 can be used as detection antibody in sandwich ELISA. HRP conjugated anti-CagA clone 5C6 can detect recombinant CagA antigen in combination with anti-CagA clone 10E9 and clone 5H10 coated wells. In addition, clone 5C6 selectively detected cell lysate of a CagA containing H. pylori strain when clone 5H10 is used as coating antibody.
Research Area	Bacteriology
Storage	Store at -20C

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 0.5mg

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Delivery expected until 12/18/2025

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