Factor IX

Human Factor IX

Reactive to human Factor IX

Human, others not tested

Factor IX is one of the key factors for blood coagulation. It can be transformed into a two-chained activated form (Factor IXa) by factors in both coagulation pathways: by Factor XIa of the contact pathway or by Factor VIIa of the tissue factor pathway. In the presence of Factor VII cofactor, Ca++ and membrane phospholipids, Factor IXa activates Factor X. The activated Factor X (Factor Xa) triggers the transformation of prothrombin to thrombin, thus results in blood coagulation. Hemophilia B is a disease caused by Factor IX deficiency.

Double distillated water is recommended to adjust the final concentration to 1.00mg/mL.

Hematology, blood coagulation.