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Anti-CD11b Antibody [5C6]

Anti-CD11b Antibody [5C6]

Item no.	ANTI-A279428-500
Manufacturer	Antibodies.com
Amount	500 ug
Category	Antibodies Flow Cytometry Immunohistochemistry Immunoprecipitation Immunofluorescence Primary Antibodies Functional Assays
Type	Antibody Primary
Format	Liquid
Applications	FC, IF, IP, IHC, FA
Clone	5C6
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host	Rat
Isotype	IgG2b
Conjugate/Tag	Unconjugated
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Available
Storage Conditions	Store undiluted at -20°C only. Storage in frost free freezers is not recommended. Avoid freeze-thaw cycles. Should this product contain a precipitate we recommend microcentrifugation before use.
Product Description	Rat monoclonal [5C6] antibody to CD11b.
Clonality	Monoclonal
Immunogen	Thioglycollate-elicited peritoneal macrophages (TPM).
Concentration	1 mg/ml
Manufacturer - Formulation	Supplied in Phosphate Buffered Saline.
Purification	Protein G affinity chromatography of tissue culture supernatant.
Recommended dilutions	Flow Cytometry: 1:100, Use 10µl of the suggested working dilution to label 10⁶ cells in 100µl
Manufacturer - Specificity	This antibody recognises CD11b, also known as the integrin alpha M chain. CD11b is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles.Rat anti Mouse CD11b antibody, clone 5C6 immunoprecipitates a heterodimer of ~165 and ~95 kDa. This clone also exhibits various functional properties, reportedly inhibiting adhesion in vitro and inflammatory recruitment in vivo. Rat anti Mouse CD11b antibody, clone 5C6 also inhibits delayed hypersensitivity, potentiates bacterial infections and inhibits type 1 diabetes.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 500 ug

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Delivery expected until 1/15/2026

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