Anti-CD29 Antibody [HM beta 1-1]

Store undiluted at -20°C only. Storage in frost free freezers is not recommended. Avoid freeze-thaw cycles.

Monoclonal

1 mg/ml

Protein G affinity chromatography of tissue culture supernatant.

This antibody recognises the murine integrin beta 1 subunit (CD29), a ~110 kDa cell surface glycoprotein that is widely expressed by a variety of cells including all leucocytes. CD29 forms non-covalent bonds with the integrin alpha subunits, including CD51 and CD49a-f, to form heterodimers. The ligands for these heterodimers include collagen, fibronectin, laminin and vascular adhesion molecule-1. In the immune system beta 1 integrins play an important role in cell adhesion, migration, activation and differentiation.Hamster anti Mouse CD29 antibody, clone HM beta 1-1 is reported to inhibit beta 1 integrin mediated adhesion.