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Anti-CD284 Antibody [HTA125]

Anti-CD284 Antibody [HTA125]

Item no.	ANTI-A280666-500
Manufacturer	Antibodies.com
Amount	500 ug
Category	Antibodies Flow Cytometry Immunoprecipitation Primary Antibodies Functional Assays
Type	Antibody Primary
Format	Liquid
Applications	FC, IP, FA
Clone	HTA125
Specific against	Human (Homo sapiens), Monkey (Cynomolgus, Simian), Guinea Pig, Dog (Canine, Canis lupus familiaris), Pig (Porcine, Sus scrofa domesticus), Cattle (Bovine), Rhesus macaque
Host	Mouse
Isotype	IgG2a
Conjugate/Tag	Unconjugated
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Available
Storage Conditions	Store undiluted at -20°C only. Storage in frost free freezers is not recommended. Avoid freeze-thaw cycles. Should this product contain a precipitate we recommend microcentrifugation before use.
Product Description	Mouse monoclonal [HTA125] antibody to TLR4.
Clonality	Monoclonal
Immunogen	Ba/F3 cell line expressing TLR4 (CD284).
Concentration	1 mg/ml
Manufacturer - Formulation	Supplied in Phosphate Buffered Saline.
Purification	Protein A affinity chromatography of tissue culture supernatant.
Recommended dilutions	Flow Cytometry: 1:10 - 1:50 Pack Size: 0.1 mg 1:25 Pack Size: 0.2 mg, Use 10µl of the suggested working dilution to label 10⁶ cells or 100µl whole blood
Manufacturer - Specificity	This antibody recognises the human Toll like receptor 4 (TLR4) cell surface antigen.TLR4, also known as CD284, has been demonstrated to act as a receptor for LPS on human monocytes and macrophages. TLR4 signalling of LPS stimulation requires the presence of the MD-2 molecule.TLR4 is weakly expressed by resting cells, but is upregulated following stimulation with LPS.This antibody has been demonstrated to block activation of monocytes with LPS. The use of a preservative free format of Mouse anti Human CD284 antibody, clone HTA125 (MCA2061EL ) is recommended for functional assays.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 500 ug

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Delivery expected until 1/15/2026

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