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Anti-TNF Alpha Antibody [MP6-XT22]

Anti-TNF Alpha Antibody [MP6-XT22]

Item no.	ANTI-A281254-500
Manufacturer	Antibodies.com
Amount	500 ug
Category	Antibodies Flow Cytometry Immunohistochemistry ELISA Primary Antibodies Immunostaining Functional Assays
Type	Antibody Primary
Format	Liquid
Applications	FC, IHC, ELISA, FA
Clone	MP6-XT22
Specific against	Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rat
Isotype	IgG1
Conjugate/Tag	Unconjugated
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Available
Storage Conditions	Store undiluted at -20°C only. Storage in frost free freezers is not recommended. Avoid freeze-thaw cycles. Should this product contain a precipitate we recommend microcentrifugation before use.
Product Description	Rat monoclonal [MP6-XT22] antibody to TNF alpha.
Clonality	Monoclonal
Immunogen	Recombinant mouse TNF alpha expressed in E. coli.
Concentration	1 mg/ml
Manufacturer - Formulation	Supplied in Phosphate Buffered Saline.
Purification	Protein G affinity chromatography of tissue culture supernatant.
Recommended dilutions	ELISA: 1 µg/ml - 10 µg/ml, FC 1: 1:10 - 1:50, Use 10µl of the suggested working dilution to label 10⁶ cells in 100µl
Manufacturer - Specificity	This antibody recognises mouse tumor necrosis factor alpha (TNF alpha), a ~17 kDa cytokine produced by monocytes, macrophages, neutrophils, NK cells and CD4+ T cells. TNF alpha forms dimers and trimers, and is also found as a ~26 kDa integral membrane protein. Mouse TNF alpha has cytolytic activity against many tumor cell lines, and has an important immunoregulatory role.Rat anti Mouse TNF alpha antibody, clone MP6-XT22 is reported to neutralize the effects of mouse TNF alpha (Gaup et al. 2008 and Yang et al. 1995).

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 500 ug

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Delivery expected until 11/13/2025

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