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Anti-CD49d Antibody [PS/2]

Anti-CD49d Antibody [PS/2]

Item no.	ANTI-A281596-500
Manufacturer	Antibodies.com
Amount	500 ug
Category	Antibodies Flow Cytometry Immunohistochemistry Immunoprecipitation Primary Antibodies Functional Assays
Type	Antibody Primary
Format	Liquid
Applications	FC, IP, IHC, FA
Clone	PS/2
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host	Rat
Isotype	IgG2b
Conjugate/Tag	Unconjugated
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Available
Storage Conditions	Store undiluted at -20°C only. Storage in frost free freezers is not recommended. Avoid freeze-thaw cycles. Should this product contain a precipitate we recommend microcentrifugation before use.
Product Description	Rat monoclonal [PS/2] antibody to Integrin alpha 4 / CD49D.
Clonality	Monoclonal
Immunogen	P815 DBA/2 murine mastocytoma cells.
Concentration	1 mg/ml
Manufacturer - Formulation	Supplied in Phosphate Buffered Saline.
Purification	Protein G affinity chromatography of tissue culture supernatant.
Recommended dilutions	Flow Cytometry: 1:50 - 1:100, Use 10µl of the suggested working dilution to label 10⁶ cells in 100µl
Manufacturer - Specificity	This antibody recognises mouse alpha 4 integrin (CD49d), a ~150 kDa single pass type I membrane glycoprotein that can associate with either beta 1 integrin (CD29) or beta 7 integrin to form heterodimers CD49d/CD29 (VLA-4) and alpha4/beta7 (LPAM-1) respectively. CD49d is expressed on most lymphocytes, granulocytes, monocytes and thymocytes. The primary ligands for CD49d are CD106 (VCAM-1), fibronectin and MAdCAM-1. Clone PS/2 has also been reported to block the binding of CD49d to its ligands.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 500 ug

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Delivery expected until 11/13/2025

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