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Anti-IL-1RA Antibody

Anti-IL-1RA Antibody

Item no.	ANTI-A283296-100
Manufacturer	Antibodies.com
Amount	100 ug
Category	Antibodies Western Blot ELISA Primary Antibodies Immunostaining Functional Assays
Type	Antibody Primary
Format	Lyophilized
Applications	WB, ELISA, FA
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Conjugate/Tag	Unconjugated
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Available
Manufacturer - Targets	IL-1RA
Storage Conditions	Lyophilized: Store at -20°C. Reconstituted: Store undiluted at -20°C, avoid freeze / thaw cycles. Storage in frost free freezers is not recommended. Should this product contain a precipitate we recommend microcentrifugation before use.
Product Description	Rabbit polyclonal antibody to IL-1RA.
Clonality	Polyclonal
Immunogen	Recombinant human IL-1RA.
Concentration	1 mg/ml after reconstitution.
Manufacturer - Formulation	Supplied in Phosphate Buffered Saline.
Recommended dilutions	ELISA: 0.5 - 2 µg/ml, Functional Assays: 2.5 - 3.7 µg/ml, WB: 0.1 - 0.2 µg/ml
Manufacturer - Specificity	This antibody recognises human Interleukin-1 receptor antagonist (IL-1RA), a naturally occurring inflammatory inhibitor protein, produced by monocytes, macrophages, neutrophils, corneal epithelial cells and fibroblasts, which inhibits the activity of IL-1 alpha and IL-1 beta, by competitively blocking binding to cell surface receptors for IL-1.Genetic variations in IL-1RA gene (IL1RN) are associated with susceptibility to microvascular complications of diabetes type 4 (MVCD4), and IL-1RA has therapeutic applications in rheumatoid arthritis, asthma, psoriasis, sepsis, chronic myelogenous leukaemia and inflammatory bowel disease.
Reconstitution	Reconstitute with 0.1 ml of distilled water. Care should be taken during reconstitution as the protein may appear as a film at the bottom of the vial. Gently mix after reconstitution. For long term storage the addition of 0.09% sodium azide is recommended. For functional studies do not add sodium azide

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ug

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Delivery expected until 11/13/2025

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