Comparison

Anti-SDF-1 Alpha Antibody European Partner

Item no. ANTI-A283936-100
Manufacturer Antibodies.com
Amount 100 ug
Category
Type Antibody Primary
Format Lyophilized
Applications WB, ELISA, IHC-P, FA
Specific against Human (Homo sapiens)
Host Rabbit
Isotype IgG
Conjugate/Tag Unconjugated
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Available
Manufacturer - Targets
SDF1 alpha
Storage Conditions
Lyophilized: Store at -20°C. Reconstituted: Store undiluted at -20°C, avoid freeze / thaw cycles. Storage in frost free freezers is not recommended. Should this product contain a precipitate we recommend microcentrifugation before use.
Product Description
Rabbit polyclonal antibody to SDF1 alpha.
Clonality
Polyclonal
Immunogen
Recombinant human SDF-1 alpha.
Concentration
1 mg/ml after reconstitution.
Manufacturer - Formulation
Supplied in Phosphate Buffered Saline.
Recommended dilutions
ELISA: 0.5 - 2 µg/ml, Functional Assays: 2.0 - 4.0 µg/ml, IHC-P: 0.5 µg/ml, WB: 0.1 - 0.2 µg/ml
Manufacturer - Specificity
This antibody recognises human SDF-1 alpha, otherwise known as CXCL12a, a 68 amino acid stromal cell derived CXC chemokine, which arises from alternative splicing of the SDF-1 gene. The two isoforms, SDF-1 alpha and SDF-1 beta, share an identical amino acid sequence, except for an additional four residues in the C-terminal region of the beta isoform.SDF-1 binds with high-affinity to the G protein–coupled receptor CXCR4 (fusin) and acts as a chemoattractant for T and B lymphocytes, monocytes and migratory neurons, and is a vital factor in haematopoiesis and angiogenesis. By competitively binding to CXCR4, SDF-1 acts as an inhibitor for the CXCR4-mediated entry of HIV-1 virus into target T-cells, and the SDF-1-CXCR4 interaction is important for the regulation of trafficking of normal and malignant stem cells.
Reconstitution
Reconstitute with 0.1 ml of distilled water. For long term storage the addition of 0.09% sodium azide is recommended. For functional studies do not add sodium azide.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 100 ug
Available: In stock
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