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MCL1 Antibody

MCL1 Antibody

Item no.	AP50001
Manufacturer	Abcepta
Amount	100 ul
Category	Antibodies Primary Antibodies
Type	Antibody Primary
Applications	WB, IHC
Specific against	other
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	MCL1, BCL2L3, Induced myeloid leukemia cell differentiation protein Mcl-1, Bcl-2-like protein 3, Bcl-2-related protein EAT/mcl1, mcl1/EAT, Bcl2-L-3
Available
Primary Accession	Q07820
Antigen Type	Synthetic Peptide
Application	WB, IHC
Bio Background	Involved in the regulation of apoptosis versus cell survival, and in the maintenance of viability but not of proliferation. Mediates its effects by interactions with a number of other regulators of apoptosis. Isoform 1 inhibits apoptosis. Isoform 2 promotes apoptosis.
Bio References	Kozopas K.M., et al.Proc. Natl. Acad. Sci. U.S.A. 90:3516-3520(1993). Umezawa A., et al.Cell Struct. Funct. 21:143-150(1996). Akgul C., et al.Cell. Mol. Life Sci. 57:684-691(2000). Bingle C.D., et al.J. Biol. Chem. 275:22136-22146(2000). Bae J., et al.J. Biol. Chem. 275:25255-25261(2000).
Clonality	Polyclonal
Gene ID	4170
Gene Name	MCL1
Subtitle	Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H, M, Rat
Legend image 1	Western blot analysis of lysate from RajI cell line, using MCL1 Antibody(C0258). C0258 was diluted at 1:1000. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody.Lysate at 35ug.
Type image 1	WB
Dilution image 1	1:1000
Legend image 2	Western blot analysis of extracts from HUVEC cells (Lane 1), JK cells (Lane 2) and COS-7 cells (Lane 3), using MCL1 Antibody. The lane on the left is treated with synthesized peptide.
Type image 2	WB
Dilution image 2	1:1000
Legend image 3	Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using MCL1 antibody .
Type image 3	IHC
Dilution image 3	1:50-1:100

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ul

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