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Caveolin-1 Antibody

Caveolin-1 Antibody

Item no.	AP50008
Manufacturer	Abcepta
Amount	100 ul
Category	Antibodies Primary Antibodies
Type	Antibody Primary
Applications	WB, IF
Specific against	other
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	Caveolin-1, CAV1, CAV
Available
Primary Accession	Q03135
Antigen Type	Synthetic Peptide
Application	WB, IF
Bio Background	May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)- mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3- dependent manner. Recruits CTNNB1 to caveolar membranes and may regulate CTNNB1-mediated signaling through the Wnt pathway.
Bio References	Glenney J.R. Jr., et al.FEBS Lett. 314:45-48(1992). Hurlstone A.F., et al.Oncogene 18:1881-1890(1999). Engelman J.A., et al.FEBS Lett. 448:221-230(1999). Kalnine N., et al.Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases. Vainonen J.P., et al.Biochem. Biophys. Res. Commun. 320:480-486(2004).
Clonality	Polyclonal
Gene ID	857
Gene Name	CAV1
Subtitle	Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H, M, Rat
Legend image 1	Immunofluorescence analysis of HuvEc cells, using Caveolin-1 antibody.
Type image 1	IF
Dilution image 1	1:100
Legend image 2	Western blot analysis of lysate from Hela cell line, using Caveolin-1 Antibody(C0139). C0139 was diluted at 1:1000. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody.Lysate at 35ug.
Type image 2	WB
Dilution image 2	1:1000
Legend image 3	Western blot analysis of extracts from HUVEC cells (Lane 1), colo cells (Lane 2) and JK cells (Lane 3), using Caveolin-1 Antibody. The lane on the left is treated with synthesized peptide.
Type image 3	WB
Dilution image 3	1:1000

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ul

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