« Back
Home /
FAS Antibody

FAS Antibody

Item no.	AP50018
Manufacturer	Abcepta
Amount	100 ul
Category	Antibodies Primary Antibodies
Type	Antibody Primary
Applications	WB, IHC
Specific against	other
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	FAS, TNFRSF6, APT1, FAS1, Tumor necrosis factor receptor superfamily member 6, Apo-1 antigen, Apoptosis-mediating surface antigen FAS, FASLG receptor, CD95
Available
Primary Accession	P25445
Antigen Type	Synthetic Peptide
Application	WB, IHC
Bio Background	Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death- inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS- mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. The secreted isoforms 2 to 6 block apoptosis (in vitro).
Bio References	Itoh N., et al.Cell 66:233-243(1991). Oehm A., et al.J. Biol. Chem. 267:10709-10715(1992). Liu C., et al.Biochem. J. 310:957-963(1995). Cascino I., et al.J. Immunol. 154:2706-2713(1995). Cascino I., et al.J. Immunol. 156:13-17(1996).
Clonality	Polyclonal
Gene ID	355
Gene Name	FAS
Subtitle	Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Legend image 1	Western blot analysis of lysate from HT-1080 cell line, using FAS Antibody(C0355). C0355 was diluted at 1:1000. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody.Lysate at 35ug.
Type image 1	WB
Dilution image 1	1:1000
Legend image 2	Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue using Fas antibody.
Type image 2	IHC
Dilution image 2	1:50-1:100

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

AP50018-datasheet.pdf

Request safety datasheet

Simple Order Order Subscription

Amount: 100 ul

available

Delivery expected until 12/4/2025

Express Delivery: Save 1 days

Compare

Add to wishlist

Get an offer