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Anti-CMBL (clone AT2B11)

Anti-CMBL (clone AT2B11)

Item no.	ARP-01-A0233
Manufacturer	American Research Products
Amount	200 ul
Category	Antibodies Primary Antibodies
Type	Antibody Monoclonal
Applications	WB, ELISA
Clone	AT2B11
Specific against	Human (Homo sapiens)
Host	Mouse
Isotype	IgG2a kappa
Citations	Ishizuka T, et al. (Apr 2010). J Biol Chem. 16,285(16):11892-902Yang X, et al. (Mar 2010). J Proteome Res. 5,9(3):1402-15.
NCBI	NP_620164
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Carboxymethylenebutenolidase homolog,
Available
Description	CMBL(carboxymethylenebutenolidase homolog) is a 245 amino acid cytosolic protein and cysteine hydrolase of the dienelactone hydrolase family that is highly expressed in liver cytosol. CMBL is the human homolog of Pseudomonas dienelactone hydrolase, a protein that participates in the bacterial halocatechol degradation pathway. That is ubiquitously expressed with high expression in liver, colon, kidney and small intestine, where it acts as a bioactivating enzyme for a prodrug type angiotensin II type 1 receptor antagonist known as olmesartan medoxomil. CMBL is inhibited by p-chloromercuribenzoate (PCMB).
Immunogen	Recombinant human CMBL (1-245aa) purified from E. coli
Form	Purified, in Phosphate-Buffered Saline (pH 7.4) with 0.1% Sodium Azide
Working Dilution	Optimal dilution should be performed by user.
Storage	Can be stored at +4C. For long term storage, aliquot and store at -20C. Avoid repeated freezing and thawing cycles.
Synonyms	Carboxymethylenebutenolidase homolog,
Concentration	0.1 mg/ml
NCBI	NP_620164
Interest Field	Metabolism
References	Ishizuka T, et al. (Apr 2010). J Biol Chem. 16, 285(16):11892-902 Yang X, et al. (Mar 2010). J Proteome Res. 5, 9(3):1402-15.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 200 ul

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Delivery expected until 8/21/2025

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