Comparison

Anti-Secretory component (free and bound)

Item no. ARP-21-1393
Manufacturer American Research Products
Amount 50 ul
Category
Type Antibody Polyclonal
Specific against Monkey (Cynomolgus, Simian)
Host Caprine
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Available
Background
Tested in immunoelectrophoresis, double radial immunodiffusion and ELISA against a panel of appropriate secretions and purified Ig isotypes. The antiserum reacts with both bound secretory component (secretory IgA) and with the free SC present in monkey secretions. In immunoelectrophoresis against monkey milk, using a high electroendosmosis agar plate, free SC is precipitated in the alph-2 region. The antiserum does not react with other molecular forms of IgA, or with any other secretory or plasma protein. In precipitating techniques as immunoelectrophoresis and single and double radial immunodiffusion to identify the presence secretory component in monkey serum or other body fluids and to determine its concentration.
Form
Delipidated, heat inactivated, in PBS and 0.1% sodium azide.
Specificity
Precipitating polyclonal Goat anti-Serum to Monkey secretory component.
Storage
Store at 4C, or in small aliquots at -20C.
Source
Secretory IgA (sIgA) functions as a dimer or polymer and accounts for almost all specific mucosal antibody activity. A molecule of sIgA is made up of two molecules of IgA, one J chain and one SC (MW 65, 000). The dimer IgA is transported into secretions by its binding to the SC on the epithelial cells. SC also has an affinity for polymeric IgM. Purified free secretory component isolated from pooled rhesus monkey milk is used for immunization.Freund's complete adjuvant is used in the first step of the immunization procedure.
Interest Fields
Veterinary
Intended Use
For Research Use Only.
Cross-reactivity
Inter-species cross-reactivity is a normal feature of antibodies to immunoglobulins, since Ig of different species frequently share antigenic determinants. Precipitation reactions have been observed with free and bound secretory component in Serum of other old-world Monkeys, including Cercopithecus, Cynomolgus and Baboon. The antiSerum may also react with other species as has been observed for Chimpanzee.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 50 ul
Available: In stock
available

Compare

Add to wishlist

Get an offer

Request delivery time

Ask a technical question

Submit a bulk request

Questions about this Product?
 
Close