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SHP-2 Antibody

SHP-2 Antibody

Item no.	BM-CAF11962-100ug
Manufacturer	Biomatik
Amount	100 UG
Category	Oncology Antibodies By Cell Type Blastoma Carcinoma Hematology Leukemia Lymphoma Melanoma Sarcoma Adenocarcinoma Immunohistochemistry Western Blot ELISA Immunofluorescence Immunocytochemistry Primary Antibodies
Type	Antibody Polyclonal
Applications	WB, IF, IHC, ICC, ELISA
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Available
Shipping Temperature	Ice packs
Storage Conditions	-20°C
Restrictions	For Research Use Only. Not for use in diagnostic procedures, drug use, or for administration to humans or animals.
Expiration	1 year
Purification	The antiserum was purified by peptide affinity chromatography.
Concentration	1 mg/ml
Comments	Acts downstream of various receptor and cytoplasmic protein tyrosine kinases to participate in the signal transduction from the cell surface to the nucleus. Positively regulates MAPK signal transduction pathway (PubMed:28074573). Dephosphorylates GAB1, ARHGAP35 and EGFR (PubMed:28074573). Dephosphorylates ROCK2 at 'Tyr-722' resulting in stimulatation of its RhoA binding activity. Dephosphorylates CDC73 (PubMed:26742426).
Immunogen	A synthesized peptide derived from human SHP-2
Technical Notes	WB: 1:500-1:2000, IHC: 1:50-1:200, IF/ICC: 1:100-1:500
Manufacturer - Gene Name	PTPN11
Manufacturer - Specificity	SHP-2 Antibody detects endogenous levels of total SHP-2

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 UG

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Delivery expected until 9/11/2025

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