CACNA1H Antibody

Ice packs

For Research Use Only. Not for use in diagnostic procedures, drug use, or for administration to humans or animals.

The antiserum was purified by peptide affinity chromatography.

Voltage-sensitive calcium channel that gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group. A particularity of this type of channel is an opening at quite negative potentials, and a voltage-dependent inactivation (PubMed:9670923, PubMed:9930755, PubMed:27149520). T-type channels serve pacemaking functions in both central neurons and cardiac nodal cells and support calcium signaling in secretory cells and vascular smooth muscle (Probable). They may also be involved in the modulation of firing patterns of neurons (PubMed:15048902). In the adrenal zona glomerulosa, participates in the signaling pathway leading to aldosterone production in response to either AGT/angiotensin II, or hyperkalemia (PubMed:25907736, PubMed:27729216).

WB 1:500ca.1:1000, IF/ICC: 1:100-1:500

CACNA1H Antibody detects endogenous levels of total CACNA1H