MNAT1 Antibody

Ice packs

For Research Use Only. Not for use in diagnostic procedures, drug use, or for administration to humans or animals.

The antiserum was purified by peptide affinity chromatography.

Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. CAK activates the cyclin-associated kinases CDK1, CDK2, CDK4 and CDK6 by threonine phosphorylation. CAK complexed to the core-TFIIH basal transcription factor activates RNA polymerase II by serine phosphorylation of the repetitive C-terminal domain (CTD) of its large subunit (POLR2A), allowing its escape from the promoter and elongation of the transcripts. Involved in cell cycle control and in RNA transcription by RNA polymerase II.

WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC: 1:100-1:500

MNAT1 Antibody detects endogenous levels of total MNAT1