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Anti-Synaptophysin/SYP PicobandÂ® Antibody

Anti-Synaptophysin/SYP PicobandÂ® Antibody

Item no.	BOS-A05049
Manufacturer	Boster
Amount	100 ug/vial
Category	Antibodies Primary Antibodies
Type	Antibody
Format	Lyophilized
Applications	WB, IF, IHC, ICC
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Citations	1. Cremin, S. M., Greer, W. L., Bodok-Nutzati, R., Schwartz, M., Peacocke, M., Siminovitch, K. A. Linkage of Wiskott-Aldrich syndrome with three marker loci, DXS426, SYP and TFE3, which map to the Xp11.3-p11.22 region. Hum. Genet. 92: 250-253, 1993. 2. Janz, R., Sudhof, T. C., Hammer, R. E., Unni, V., Siegelbaum, S. A., Bolshakov, V. Y. Essential roles in synaptic plasticity for synaptogyrin I and synaptophysin I. Neuron 24: 687-700, 1999. 3. Kwon, S. E., Chapman, E. R. Synaptophysin regulates the kinetics of synaptic vesicle endocytosis in central neurons. Neuron 70: 847-854, 2011.
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Synaptophysin; Major synaptic vesicle protein p38; SYP
Available
Manufacturer - Category	Primary Antibodies
Manufacturer - Isotype	Rabbit IgG
Storage Conditions	Store at -20Â°C for one year from date of receipt. After reconstitution, at 4Â°C for one month. It can also be aliquotted and stored frozen at -20Â°C for six months. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight	38 kDa
Calculated Molecular weight	25847 MW
Clonality	Polyclonal
Application Details	Western blot, 0.1-0.25?g/ml, Mouse, Rat Immunohistochemistry(Paraffin-embedded Section, 2-5 ?g/ml, Human, Mouse, Rat Immunocytochemistry/Immunofluorescence, 5?g/ml, Human Immunofluorescence, 5?g/ml, Mouse, Rat
Manufacturer - Gene Name	SYP
Gene Full Name	synaptophysin
Manufacturer - Specificity	No cross reactivity with other proteins.
Background	Synaptophysin, also known as the major synaptic vesicle protein p38, is a protein that in humans is encoded by the SYP gene. It is mapped to Xp11.23. This gene encodes an integral membrane protein of small synaptic vesicles in brain and endocrine cells. The protein also binds cholesterol and is thought to targeting of vesicle-associated membrane protein 2 (synaptobrevin) to intracellular compartments. Mutations in this gene are associated with an X-linked form of cognitive disability.
Immunogen	A synthetic peptide corresponding to a sequence at the N-terminus of human Synaptophysin/SYP, which shares 91.3% amino acid (aa) sequence identity with both mouse and rat Synaptophysin/SYP.
Contents	Each vial contains 4 mg Trehalose, 0.9mg NaCl, 0.2mg Na₂HPO₄, 0.05 mg NaN₃.
Purification	Immunogen affinity purified.
Reconstitution	Add 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ?g/ml.
Manufacturer - Research Category	Angiogenesis, Cardiovascular, Cytokines, Immunology, Innate Immunity
Protein Name	Uncharacterized protein
Protein Function	Possibly involved in structural functions as organizing other membrane components or in targeting the vesicles to the plasma membrane. Involved in the regulation of short-term and long-term synaptic plasticity.
Subcellular Localization	Synaptic vesicle membrane. Multi-pass membrane protein. Synaptosome.
Description	Boster Bio Anti-Synaptophysin/SYP Picoband® Antibody catalog # A05049. Tested in IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Tissue Specificity	Ubiquitous in adult tissues. Detected in osteoblasts of the perichondrium in the developing limb of 12-week old embryos. Isoform 1 is detected in fetal brain, lung, kidney and testis. Isoform 2 is detected in fetal testis, and at much lower levels in fetal brain, lung and kidney.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

BOS-A05049-datasheet.pdf

BOS-A05049-safety-datasheet.pdf