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Anti-NSD3 Antibody Picoband®

Anti-NSD3 Antibody Picoband®

Item no.	BOS-A32443-1
Manufacturer	Boster
Amount	100 ug/vial
Category	Antibodies Primary Antibodies
Type	Antibody
Format	Lyophilized
Applications	WB, ELISA
Specific against	Human (Homo sapiens), Monkey (Cynomolgus, Simian)
Host	Rabbit
Isotype	IgG
Citations	1. Angrand, P.-O., Apiou, F., Stewart, A. F., Dutrillaux, B., Losson, R., Chambon, P. NSD3, a new SET domain-containing gene, maps to 8p12 and is amplified in human breast cancer cell lines. Genomics 74: 79-88, 2001. 2. Rosati, R., La Starza, R., Veronese, A., Aventin, A., Schwienbacher, C., Vallespi, T., Negrini, M., Martelli, M. F., Mecucci, C. NUP98 is fused to the NSD3 gene in acute myeloid leukemia associated with t(8;11)(p11.2;p15). Blood 99: 3857-3860, 2002. Note: Erratum: Blood 100: 1132 only, 2002. 3. Stec, I., van Ommen, G.-J. B., den Dunnen, J. T. WHSC1L1, on human chromosome 8p11.2, closely resembles WHSC1 and maps to a duplicated region shared with 4p16.3. Genomics 76: 5-8, 2001.
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Protein Bop; BH3-only protein; Retrotransposon Gag-like protein 10; RTL10; BOP, C22orf29
Available
Manufacturer - Category	Primary Antibodies
Manufacturer - Isotype	Rabbit IgG
Storage Conditions	At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
Observed Molecular Weight	90 kDa
Calculated Molecular weight	14377 MW
Clonality	Polyclonal
Application Details	Western blot, 0.25-0.5 ?g/ml, Human, Monkey ELISA, 0.1-0.5 ?g/ml, -
Manufacturer - Gene Name	NSD3
Gene Full Name	retrotransposon Gag like 10
Background	Histone-lysine N-methyltransferase NSD3 is an enzyme that in humans is encoded by the WHSC1L1 gene. This gene is related to the Wolf-Hirschhorn syndrome candidate-1 gene and encodes a protein with PWWP (proline-tryptophan-tryptophan-proline) domains. This protein methylates histone H3 at lysine residues 4 and 27, which represses gene transcription. Two alternatively spliced variants have been described.
Immunogen	E.coli-derived human NSD3 recombinant protein (Position: Q46-K1425).
Contents	Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
Purification	Immunogen affinity purified.
Reconstitution	Adding 0.2 ml of distilled water will yield a concentration of 500 ?g/ml.
Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ?g/ml.
Manufacturer - Research Category	Chemokines, Immunology, Innate Immunity
Protein Name	Lymphocyte antigen 6A-2/6E-1
Protein Function	Could induce apoptosis in a BH3 domain-dependent manner. The interaction network of Bcl-2 family members may play a key role in modulation RTL10/BOP intrinsic apoptotic signaling activity.
Subcellular Localization	Cell membrane; Lipid-anchor, GPI-anchor.
Description	Boster Bio Anti-NSD3 Antibody Picoband® catalog # A32443-1. Tested in ELISA, WB applications. This antibody reacts with Human, Monkey. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Tissue Specificity	Ubiquitously expressed.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

BOS-A32443-1-datasheet.pdf

BOS-A32443-1-safety-datasheet.pdf