Item no. |
BOS-M04615-5 |
Manufacturer |
Boster
|
Amount |
100 ul/vial |
Category |
|
Type |
Antibody Monoclonal |
Format |
Liquid |
Applications |
WB |
Clone |
18A77 |
Specific against |
Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus) |
Host |
Rabbit |
Isotype |
IgG |
Sensitivity |
>5000 cells |
ECLASS 10.1 |
42030590 |
ECLASS 11.0 |
42030590 |
UNSPSC |
12352203 |
Alias |
Caldesmon;CDM;CALD1;CAD, CDM; |
Available |
|
Manufacturer - Category |
Rabbit Monoclonal Antibodies |
Storage Conditions |
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles. |
Observed Molecular Weight |
130 kDa |
Calculated Molecular weight |
93231 MW |
Clonality |
Monoclonal |
Application Details |
WB 1:500-1:2000 |
Manufacturer - Gene Name |
ALDH1L1 |
Gene Full Name |
Caldesmon |
Immunogen |
A synthesized peptide derived from human ALDH1L1 |
Contents |
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5 mg/ml BSA. |
Purification |
Affinity-chromatography |
Reconstitution |
Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL |
Concentration |
Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure. |
Manufacturer - Research Category |
DNA/RNA, Epigenetics and Nuclear Signaling, RNA Processing |
Protein Name |
T-cell surface glycoprotein CD3 zeta chain |
Protein Function |
Actin- and myosin-binding protein implicated in the regulation of actomyosin interactions in smooth muscle and nonmuscle cells (could act as a bridge between myosin and actin filaments). Stimulates actin binding of tropomyosin which increases the stabilization of actin filament structure. In muscle tissues, inhibits the actomyosin ATPase by binding to F-actin. This inhibition is attenuated by calcium-calmodulin and is potentiated by tropomyosin. Interacts with actin, myosin, two molecules of tropomyosin and with calmodulin. Also play an essential role during cellular mitosis and receptor capping. Involved in Schwann cell migration during peripheral nerve regeneration (By similarity). |
Subcellular Localization |
Cytoplasm, cytoskeleton. Cytoplasm, myofibril. On thin filaments in smooth muscle and on stress fibers in fibroblasts (nonmuscle). |
Description |
Boster Bio Anti-ALDH1L1 Rabbit Monoclonal Antibody catalog # M04615-5. Tested in WB application. This antibody reacts with Human, Mouse, Rat. |
Tissue Specificity |
High-molecular-weight caldesmon (isoform 1) is predominantly expressed in smooth muscles, whereas low-molecular- weight caldesmon (isoforms 2, 3, 4 and 5) are widely distributed in non-muscle tissues and cells. Not expressed in skeletal muscle or heart. |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.