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Anti phospho TDP-43 (pS409/410) pAb [replaces CAC-TIP-PTD-P01]

Anti phospho TDP-43 (pS409/410) pAb [replaces CAC-TIP-PTD-P01]

Item no.	CAC-TIP-PTD-P07
Manufacturer	Cosmobio
Amount	100 ul
Category	Neuroscience Molecular Targets for Neuroscience Targets for Rodent Neurosciences Aging & Neurological Disorders Protein Aggregation, Clearance & Misfolding Antibodies Immunohistochemistry Western Blot ELISA Primary Antibodies
Type	Antibody Polyclonal
Format	Liquid
Applications	WB, IHC, ELISA
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Available
Manufacturer - Category	Antibodies/Primary Antibodies/Cell Biology/Gene Expression & Transcription; Antibodies/Primary Antibodies/Cell Biology/Protein Synthesis; Antibodies/Primary Antibodies/Cell Biology/RNA Processing; Antibodies/Primary Antibodies/Cell Types/Neurons; Antibodies/Primary Antibodies/Disease/Acquired Immunodeficiency Syndrome; Antibodies/Primary Antibodies/Disease/Alzheimer's Disease; Antibodies/Primary Antibodies/Disease/Amyotrophic Lateral Sclerosis; Antibodies/Primary Antibodies/Disease/Cystic Fibrosis; Antibodies/Primary Antibodies/Disease/Frontotemporal Dementia; Antibodies/Primary Antibodies/Neurobiology/Neurodegeneration; Research Area/Cell Biology/Gene Expression & Transcription/Primary Antibodies; Research Area/Cell Biology/Protein Synthesis/Primary Antibodies; Research Area/Cell Biology/RNA Processing/Primary Antibodies; Research Area/Cell Types/Neurons/Primary Antibodies; Research Area/Disease/Acquired Immunodeficiency Syndrome/Primary Antibodies; Research Area/Disease/Alzheimer's Disease/Primary Antibodies; Research Area/Disease/Amyotrophic Lateral Sclerosis/Primary Antibodies; Research Area/Disease/Cystic Fibrosis/Primary Antibodies; Research Area/Disease/Frontotemporal Dementia/Primary Antibodies; Research Area/Neurobiology/Neurodegeneration/Primary Antibodies
Maker	CAC
Short Description	Format: Ammonium sulfate precipitated serum (Ig fraction) in 50% glycerol with azide preservative. Prepared from fresh rabbits immunized with a peptide identical to the very popular, but sold out, CAC-TIP-PTD-PO1 that was sold as diluted serum.
Description	TDP-43, a heterogeneous nuclear ribonucleoprotein, was identified as a component of ubiquitin-positive and tau-negative inclusions observed in cases of frontotemporal lobar degeneration (FTLD-U) and amyotrophic lateral sclerosis (ALS). Immunochemical analyses using antibodies generated against phospho- and non-phosphopeptides of human TDP-43 revealed that abnormally phosphorylated full-length TDP-43 (45 kDa), C-terminal fragments (~25 kDa) and smearing substances are deposited as intracellular inclusions in affected regions of FTLD-U and ALS cases. These antibodies are powerful tools for biochemical and immunohistochemical analyses of neurodegenerative diseases and for evaluation of cellular or animal models of TDP-43 proteinopathy.
Purification	Ammonium Sulfate
Clonality	Polyclonal

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

CAC-TIP-PTD-P07.pdf

CAC-TIP-PTD-P07-datasheet.pdf

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Amount: 100 ul

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Delivery expected until 9/11/2025

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