Comparison

CD271 Unconjugated

Item no. CAT-111901
Manufacturer Caprico Biotechnologies
Amount 100 ug
Category
Type Antibody Monoclonal
Format PBS, pH7.2, 0.09% NaN3 and 0.2% (w/v) BSA
Clone ME20.4
Specific against Human (Homo sapiens)
Host Mouse
Isotype IgG1 kappa
Conjugate/Tag Unconjugated
Purity >95%
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Available
Immunogen
WM245 melanoma cells
Antigen
CD271
Clonality
Monoclonal
Long Description (4000 Characters)
The clone ME20.4, a mouse monoclonal antibody selectively binds with a ~75 kD type I transmembrane protein known as CD271. It is also known as the nerve growth factor receptor (NGFR) and a member of the tumor necrosis factor receptor (TNFR) superfamily.  Various cell types express CD271 including neuronal axons, Schwann cells, mesenchymal stem cells, epithelial cells, etc.  Increased levels of CD271 were observed in brain metastatic melanoma cells and in lung-metastasizing melanoma cells. It is a transmembrane signaling receptor involved in negative cell cycle regulation and is specific for neural crest origin.
Primary/Secondary
Primary
Product Descriptions
CD271 Unconjugated
Status
RUO
Storage & Shipping Conditions
2-8oC

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 100 ug
Available: In stock
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