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ACOX1 antibody

ACOX1 antibody

Item no.	FNab00095-100ug
Manufacturer	FineTest
Amount	100 ug
Category	Antibodies Primary Antibodies
Type	Antibody Monoclonal
Format	Liquid
Applications	WB, IF, IHC, ELISA
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Purity	≥95% as determined by SDS-PAGE
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Peroxisomal acyl-coenzyme A oxidase 1 (AOX),Palmitoyl-CoA oxidase,Peroxisomal fatty acyl-CoA oxidase,Straight-chain acyl-CoA oxidase (SCOX),Peroxisomal acyl-CoA oxidase 1,A chain,Peroxisomal acyl-CoA oxidase 1,B chain,Peroxisomal acyl-CoA oxidase 1,C chain,ACOX1,ACOX
Available
Manufacturer - Targets	ACOX1
Storage Conditions	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Background	The protein encoded by this gene is the first enzyme of the fatty acid beta-oxidation pathway, which catalyzes the desaturation of acyl-CoAs to 2-trans-enoyl-CoAs. It donates electrons directly to molecular oxygen, thereby producing hydrogen peroxide. Defects in this gene result in pseudoneonatal adrenoleukodystrophy, a disease that is characterized by accumulation of very long chain fatty acids. Alternatively spliced transcript variants encoding different isoforms have been identified.It has 3 isoforms produced by alternative splicing with the molecular mass of 70-74 kDa and can be cleaved post-translationally into a 50-kDa and a 22-kDa subunit between Val468 and Ala469 (PMID: 10672038).
Clonality	polyclonal
Immunogen	acyl-Coenzyme A oxidase 1, palmitoyl
Observed MW	74 kDa
Purification	Immunogen affinity purified
Recommended dilution	WB: 1:500 - 1:2000; IHC: 1:100 - 1:200; IF: 1:50 - 1:200
Manufacturer - Research Area	Metabolism, Developmental biology
Manufacturer - Synonym	Peroxisomal acyl-coenzyme A oxidase 1 (AOX), Palmitoyl-CoA oxidase, Peroxisomal fatty acyl-CoA oxidase, Straight-chain acyl-CoA oxidase (SCOX), Peroxisomal acyl-CoA oxidase 1, A chain, Peroxisomal acyl-CoA oxidase 1, B chain, Peroxisomal acyl-CoA oxidase 1, C chain, ACOX1, ACOX

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