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anti- ATG4C antibody

anti- ATG4C antibody

Manufacturer	FineTest
Category	Antibodies Primary Antibodies
Type	Antibody Monoclonal
Specific against	Human, Mouse
Isotype	IgG
Format	liquid
Amount	100ug
Host	Rabbit
Item no.	FNab00675-100ug
eClass 6.1	32160702
eClass 9.0	42030590
Available
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Clonality	polyclonal
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20C for 12 months(Avoid repeated freeze / thaw cycles.)
Background	Cysteine protease required for the cytoplasm to vacuole transport(Cvt) and autophagy. Is not essential for autophagy development under normal conditions but is required for a proper autophagic response under stressful conditions such as prolonged starvation(By similarity). Cleaves the C-terminal amino acid of ATG8 family proteins MAP1LC3 and GABARAPL2, to reveal a C-terminal glycine. Exposure of the glycine at the C-terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine(PE) and insertion to membranes, which is necessary for autophagy. Has also an activity of delipidating enzyme for the PE-conjugated forms.
Immunogen	ATG4 autophagy related 4 homolog C(S. cerevisiae)
Observed MW	52-55 kDa
Uniprot ID	Q96DT6
Tested Application	ELISA, WB, IHC, IF
Recommended dilution	WB: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200
Gene ID	84938
Research Area	Cardiovascular, Metabolism

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100ug

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Delivery expected until 5/23/2024